The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial.
Ma L, Hu X, Song L, Chen X, Ouyang M, Billot L, Li Q, Malavera A, Li X, Muñoz-Venturelli P, de Silva A, Thang NH, Wahab KW, Pandian JD, Wasay M, Pontes-Neto OM, Abanto C, Arauz A, Shi H, Tang G, Zhu S, She X, Liu L, Sakamoto Y, You S, Han Q, Crutzen B, Cheung E, Li Y, Wang X, Chen C, Liu F, Zhao Y, Li H, Liu Y, Jiang Y, Chen L, Wu B, Liu M, Xu J, You C, Anderson CS; INTERACT3 Investigators.
Ma L, et al.
Lancet. 2023 Jul 1;402(10395):27-40. doi: 10.1016/S0140-6736(23)00806-1. Epub 2023 May 25.
Lancet. 2023.
PMID: 37245517
Free PMC article.
Clinical Trial.
The likelihood of a poor functional outcome was lower in the care bundle group (common odds ratio 0.86; 95% CI 0.76-0.97; p=0.015). The favourable shift in mRS scores in the care bundle group was generally consistent across a range of sensitivity analyses that included add …
The likelihood of a poor functional outcome was lower in the care bundle group (common odds ratio 0.86; 95% CI 0.76-0.97; p=0.015). T …