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Page 1
Did you mean P. dobbins (405 results)?
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis.
Fox RJ, Coffey CS, Conwit R, Cudkowicz ME, Gleason T, Goodman A, Klawiter EC, Matsuda K, McGovern M, Naismith RT, Ashokkumar A, Barnes J, Ecklund D, Klingner E, Koepp M, Long JD, Natarajan S, Thornell B, Yankey J, Bermel RA, Debbins JP, Huang X, Jagodnik P, Lowe MJ, Nakamura K, Narayanan S, Sakaie KE, Thoomukuntla B, Zhou X, Krieger S, Alvarez E, Apperson M, Bashir K, Cohen BA, Coyle PK, Delgado S, Dewitt LD, Flores A, Giesser BS, Goldman MD, Jubelt B, Lava N, Lynch SG, Moses H, Ontaneda D, Perumal JS, Racke M, Repovic P, Riley CS, Severson C, Shinnar S, Suski V, Weinstock-Guttman B, Yadav V, Zabeti A; NN102/SPRINT-MS Trial Investigators. Fox RJ, et al. N Engl J Med. 2018 Aug 30;379(9):846-855. doi: 10.1056/NEJMoa1803583. N Engl J Med. 2018. PMID: 30157388 Free PMC article. Clinical Trial.
The rate of change in the brain parenchymal fraction was -0.0010 per year with ibudilast and -0.0019 per year with placebo (difference, 0.0009; 95% confidence interval, 0.00004 to 0.0017; P=0.04), which represents approximately 2.5 ml less brain-tissue loss with ibudilast …
The rate of change in the brain parenchymal fraction was -0.0010 per year with ibudilast and -0.0019 per year with placebo (difference, 0.00 …
The relationship between diffusion heterogeneity and microstructural changes in high-grade gliomas using Monte Carlo simulations.
Lee CY, Bennett KM, Debbins JP, Choi IY, Lee P. Lee CY, et al. Magn Reson Imaging. 2022 Jan;85:108-120. doi: 10.1016/j.mri.2021.10.001. Epub 2021 Oct 13. Magn Reson Imaging. 2022. PMID: 34653578
CONCLUSION: Among simulated microstructural changes, only increases in cell density at low P(mem) or decreases in P(mem) corresponded to both the decreased diffusivity and increased diffusion heterogeneity measures. The results suggest that increases in cell density …
CONCLUSION: Among simulated microstructural changes, only increases in cell density at low P(mem) or decreases in P(mem) corre …
Development of a dosimeter prototype with machine learning based 3-D dose reconstruction capabilities.
Finneman GM, Eichhorn OH, Meskell NR, Caplice TW, Benson AD, Abu-Halawa AS, Ademoski GL, Clark AC, Gayer DS, Hendrickson KN, Debbins PA, Onel Y, Ayan AS, Akgun U. Finneman GM, et al. Biomed Phys Eng Express. 2021 Nov 23;8(1). doi: 10.1088/2057-1976/ac396c. Biomed Phys Eng Express. 2021. PMID: 34768242
The active material of the prototype dosimeter is a blend of radiation-hard peroxide-cured polysiloxane plastic doped with scintillating agent P-Terphenyl and wavelength-shifter BisMSB. The prototype detector was tested with 6 MV and 10 MV x-ray beams at Ohio State Univers …
The active material of the prototype dosimeter is a blend of radiation-hard peroxide-cured polysiloxane plastic doped with scintillating age …
Scan-rescan repeatability and cross-scanner comparability of DTI metrics in healthy subjects in the SPRINT-MS multicenter trial.
Zhou X, Sakaie KE, Debbins JP, Narayanan S, Fox RJ, Lowe MJ. Zhou X, et al. Magn Reson Imaging. 2018 Nov;53:105-111. doi: 10.1016/j.mri.2018.07.011. Epub 2018 Jul 23. Magn Reson Imaging. 2018. PMID: 30048675 Free PMC article.

Significant differences were also observed for SNR when comparing GE scanners and Siemens Skyra scanners (p < 1.4e-7) and when comparing Siemens Skyra scanners and TIM Trio scanners (p < 1.0e-10). ...The measured signal intensity from a background noise region

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Significant differences were also observed for SNR when comparing GE scanners and Siemens Skyra scanners (p < 1.4e-7) and when com

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Cerebral blood flow in Alzheimer's disease.
Roher AE, Debbins JP, Malek-Ahmadi M, Chen K, Pipe JG, Maze S, Belden C, Maarouf CL, Thiyyagura P, Mo H, Hunter JM, Kokjohn TA, Walker DG, Kruchowsky JC, Belohlavek M, Sabbagh MN, Beach TG. Roher AE, et al. Vasc Health Risk Manag. 2012;8:599-611. doi: 10.2147/VHRM.S34874. Epub 2012 Oct 23. Vasc Health Risk Manag. 2012. PMID: 23109807 Free PMC article.
The AD group had a significantly lower pulse pressure (mean AD 48, mean NDC 71; P = 0.0004). A significant group difference was also observed in their hippocampal volumes. Composite z-scores for clinical, psychometric, hippocampal volume, and hemodynamic data differed betw …
The AD group had a significantly lower pulse pressure (mean AD 48, mean NDC 71; P = 0.0004). A significant group difference was also …
Cardiac magnetic resonance fluoroscopy.
Debbins JP, Riederer SJ, Rossman PJ, Grimm RC, Felmlee JP, Breen JF, Ehman RL. Debbins JP, et al. Magn Reson Med. 1996 Oct;36(4):588-95. doi: 10.1002/mrm.1910360414. Magn Reson Med. 1996. PMID: 8892212
Influence of equipment changes on MRI measures of brain atrophy and brain microstructure in a placebo-controlled trial of ibudilast in progressive multiple sclerosis.
Sakaie K, Fedler JK, Yankey JW, Nakamura K, Debbins J, Lowe MJ, Raska P, Fox RJ. Sakaie K, et al. Mult Scler J Exp Transl Clin. 2021 May 18;7(2):20552173211010843. doi: 10.1177/20552173211010843. eCollection 2021 Apr-Jun. Mult Scler J Exp Transl Clin. 2021. PMID: 34046185 Free PMC article.

A switch from GE HDxt to Siemens Skyra led to significant shifts in BPF (p < 0.04) and TD (p < 0.0001). However, we could not detect the influence of hardware changes on overall trial outcomes- differences between placebo and treatment arms in change over time

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A switch from GE HDxt to Siemens Skyra led to significant shifts in BPF (p < 0.04) and TD (p < 0.0001). However, we coul

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The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods.
Jack CR Jr, Bernstein MA, Fox NC, Thompson P, Alexander G, Harvey D, Borowski B, Britson PJ, L Whitwell J, Ward C, Dale AM, Felmlee JP, Gunter JL, Hill DL, Killiany R, Schuff N, Fox-Bosetti S, Lin C, Studholme C, DeCarli CS, Krueger G, Ward HA, Metzger GJ, Scott KT, Mallozzi R, Blezek D, Levy J, Debbins JP, Fleisher AS, Albert M, Green R, Bartzokis G, Glover G, Mugler J, Weiner MW. Jack CR Jr, et al. J Magn Reson Imaging. 2008 Apr;27(4):685-91. doi: 10.1002/jmri.21049. J Magn Reson Imaging. 2008. PMID: 18302232 Free PMC article.
23 results