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Recent advances of the Povarov reaction in medicinal chemistry.
Ghashghaei O, Masdeu C, Alonso C, Palacios F, Lavilla R. Ghashghaei O, et al. Drug Discov Today Technol. 2018 Nov;29:71-79. doi: 10.1016/j.ddtec.2018.08.004. Epub 2018 Aug 28. Drug Discov Today Technol. 2018. PMID: 30471676 Review.
A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death.
Barth ND, Mendive-Tapia L, Subiros-Funosas R, Ghashghaei O, Lavilla R, Maiorino L, He XY, Dransfield I, Egeblad M, Vendrell M. Barth ND, et al. Among authors: ghashghaei o. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202113020. doi: 10.1002/anie.202113020. Epub 2021 Dec 16. Angew Chem Int Ed Engl. 2022. PMID: 34762762 Free PMC article.
The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.
Sánchez-Vera I, Saura-Esteller J, Núñez-Vázquez S, Cosialls AM, Ghashghaei O, Lavilla R, Pons G, Gil J, Iglesias-Serret D. Sánchez-Vera I, et al. Among authors: ghashghaei o. Biochem Pharmacol. 2023 Dec;218:115860. doi: 10.1016/j.bcp.2023.115860. Epub 2023 Oct 24. Biochem Pharmacol. 2023. PMID: 37884196 Free article.
Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds.
Nadal Rodríguez P, Ghashghaei O, Schoepf AM, Benson S, Vendrell M, Lavilla R. Nadal Rodríguez P, et al. Among authors: ghashghaei o. Angew Chem Weinheim Bergstr Ger. 2023 Oct 9;135(41):e202303889. doi: 10.1002/ange.202303889. Epub 2023 Jun 2. Angew Chem Weinheim Bergstr Ger. 2023. PMID: 38516006 Free PMC article.
18 results