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Page 1
What is the current value of fluorescence polarization assays in small molecule screening?
Expert Opin Drug Discov. 2020 Feb;15(2):131-133. doi: 10.1080/17460441.2020.1702966. Epub 2019 Dec 13.
Expert Opin Drug Discov. 2020.
PMID: 31833421
No abstract available.
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.
Nonga OE, Lavogina D, Enkvist E, Kestav K, Chaikuad A, Dixon-Clarke SE, Bullock AN, Kopanchuk S, Ivan T, Ekambaram R, Viht K, Knapp S, Uri A.
Nonga OE, et al.
Molecules. 2021 Jul 19;26(14):4353. doi: 10.3390/molecules26144353.
Molecules. 2021.
PMID: 34299628
Free PMC article.
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Discovery of strong inhibitory properties of a monoclonal antibody of PKA and use of the antibody and a competitive photoluminescent orthosteric probe for analysis of the protein kinase.
Nonga OE, Lavogina D, Ivan T, Viht K, Enkvist E, Uri A.
Nonga OE, et al.
Biochim Biophys Acta Proteins Proteom. 2020 Aug;1868(8):140427. doi: 10.1016/j.bbapap.2020.140427. Epub 2020 Apr 10.
Biochim Biophys Acta Proteins Proteom. 2020.
PMID: 32283249
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Inhibitors and fluorescent probes for protein kinase PKAcβ and its S54L mutant, identified in a patient with cortisol producing adenoma.
Nonga OE, Enkvist E, Herberg FW, Uri A.
Nonga OE, et al.
Biosci Biotechnol Biochem. 2020 Sep;84(9):1839-1845. doi: 10.1080/09168451.2020.1772038. Epub 2020 Jun 7.
Biosci Biotechnol Biochem. 2020.
PMID: 32507034
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