Preliminary results with non-centrifuged autologous fat graft and percutaneous aponeurotomy for treating Dupuytren's disease

Hand Surg Rehabil. 2017 Oct;36(5):350-354. doi: 10.1016/j.hansur.2017.05.004. Epub 2017 Jul 18.

Abstract

The aim of this study was to describe our experience with treating Dupuytren's disease using needle aponeurotomy and non-centrifuged autologous fat grafting. The study included 17 patients (18 hands). Patients were treated with needle aponeurotomy and non-centrifuged autologous fat graft under general anesthesia. The fat grafts were injected into the surgical area so as to stay in contact with the operated site. An extension splint was used for 1 week postoperatively and the patients received hand therapy for 3 weeks. Before the treatment, the contracture in the proximal interphalangeal and metacarpophalangeal joints was a mean of 45.06 ± 13.44 degrees and 36.56 ± 13.09 degrees, respectively. It was 1.61 ± 1.65 and -0.56 ± 3.78 degrees at 3 months, respectively. The difference between these measurements was statistically significant. The mean follow-up period was 12 months. The results were satisfactory and no complications were observed during the follow-up period. Based on the results of the study, percutaneous aponeurotomy with non-centrifuged autologous fat grafting was found to have significantly beneficial effects in the treatment of Dupuytren's disease.

Keywords: Aiguille; Aponeurotomy; Aponévrotomie; Contracture; Dupuytren; Fat graft; Greffe de tissus adipeux; Needle; Rétraction.

MeSH terms

  • Adipose Tissue / transplantation*
  • Aponeurosis / surgery*
  • Dupuytren Contracture / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Needles*
  • Orthopedic Procedures*
  • Physical Therapy Modalities
  • Postoperative Care
  • Retrospective Studies
  • Splints