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Page 1
What's new on CDC25 phosphatase inhibitors.
Contour-Galcera MO, Sidhu A, Prévost G, Bigg D, Ducommun B. Contour-Galcera MO, et al. Pharmacol Ther. 2007 Jul;115(1):1-12. doi: 10.1016/j.pharmthera.2007.03.009. Epub 2007 Apr 21. Pharmacol Ther. 2007. PMID: 17531323 Review.
But some inhibitors can combine in the same molecule several of these mechanisms, thus by fitting into the active site of the enzyme through one part of the molecule and bringing the reactive moiety in close proximity to the catalytic cysteine. This review summarizes novel …
But some inhibitors can combine in the same molecule several of these mechanisms, thus by fitting into the active site of the enzyme through …
Automatic extraction of the mitral valve chordae geometry for biomechanical simulation.
Panicheva D, Villard PF, Hammer PE, Perrin D, Berger MO. Panicheva D, et al. Int J Comput Assist Radiol Surg. 2021 May;16(5):709-720. doi: 10.1007/s11548-021-02368-3. Epub 2021 May 12. Int J Comput Assist Radiol Surg. 2021. PMID: 33978895
The method has also been tested within a structural simulation of the mitral valve closed state. CONCLUSION: Our results show that the chordae architecture resulting from our algorithm can give results similar to experienced users while providing an equivalent biomechanica …
The method has also been tested within a structural simulation of the mitral valve closed state. CONCLUSION: Our results show that th …
Chronic food restriction in mice and increased systemic ghrelin induce preference for running wheel activity.
Tezenas du Montcel C, Cao J, Mattioni J, Hamelin H, Lebrun N, Ramoz N, Gorwood P, Tolle V, Viltart O. Tezenas du Montcel C, et al. Psychoneuroendocrinology. 2023 Sep;155:106311. doi: 10.1016/j.psyneuen.2023.106311. Epub 2023 Jun 7. Psychoneuroendocrinology. 2023. PMID: 37295225 Free article.
CONCLUSIONS: These data provide evidence that food restriction-induced physical activity is closely correlated with metabolic adaptations to nutritional status implicating ghrelin in the quantity of physical activity....
CONCLUSIONS: These data provide evidence that food restriction-induced physical activity is closely correlated with metabolic adaptat …
Safe disconnection of 5-fluorouracil elastomeric pumps: The benefit of a closed-system-transfer device designed for cytotoxic drug administration/perfusion.
Raphaëlle P, Elodie P, Nathalie J, Odile A, Paul S, Isabelle M, Hélène L. Raphaëlle P, et al. J Vasc Access. 2023 Jul;24(4):653-659. doi: 10.1177/11297298211044017. Epub 2021 Sep 18. J Vasc Access. 2023. PMID: 34538108
This study was designed to evaluate the risk of 5-fluorouracil (5-FU) contamination for nurses when disconnecting the infusion line of an elastomeric pump from a non-coring needle, by comparing three configurations: the first one using standard Male and Female Luer lock (Group 1) …
This study was designed to evaluate the risk of 5-fluorouracil (5-FU) contamination for nurses when disconnecting the infusion line of an el …
A folding switch regulates interleukin 27 biogenesis and secretion of its α-subunit as a cytokine.
Müller SI, Friedl A, Aschenbrenner I, Esser-von Bieren J, Zacharias M, Devergne O, Feige MJ. Müller SI, et al. Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1585-1590. doi: 10.1073/pnas.1816698116. Epub 2019 Jan 16. Proc Natl Acad Sci U S A. 2019. PMID: 30651310 Free PMC article.
This provides the basis for a more human-like IL-27 system in mice and establishes a secretion-competent human IL-27alpha that signals on its own and can regulate immune cell function. Taken together, our data reveal a close link between protein folding and immunoregulatio …
This provides the basis for a more human-like IL-27 system in mice and establishes a secretion-competent human IL-27alpha that signals on it …
Functional analysis of monoclonal antibodies against the Plasmodium falciparum PfEMP1-VarO adhesin.
Guillotte M, Nato F, Juillerat A, Hessel A, Marchand F, Lewit-Bentley A, Bentley GA, Vigan-Womas I, Mercereau-Puijalon O. Guillotte M, et al. Malar J. 2016 Jan 15;15:28. doi: 10.1186/s12936-015-1016-5. Malar J. 2016. PMID: 26772184 Free PMC article.
Based on competition ELISA and binding to mutant DBL1 domains, two distinct binding sites for rosette-disrupting mAbs were identified in close proximity to the RBC-binding site. CONCLUSIONS: Rosette-inhibitory antibodies bind to conformation-dependent epitopes located c
Based on competition ELISA and binding to mutant DBL1 domains, two distinct binding sites for rosette-disrupting mAbs were identified in …
NMR chemical shift analysis decodes olefin oligo- and polymerization activity of d0 group 4 metal complexes.
Gordon CP, Shirase S, Yamamoto K, Andersen RA, Eisenstein O, Copéret C. Gordon CP, et al. Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E5867-E5876. doi: 10.1073/pnas.1803382115. Epub 2018 Jun 11. Proc Natl Acad Sci U S A. 2018. PMID: 29891699 Free PMC article.
This molecular orbital picture establishes a connection between olefin insertion into a metal-alkyl bond and olefin metathesis and a close link between the Cossee-Arlmann and Green-Rooney polymerization mechanisms. ...
This molecular orbital picture establishes a connection between olefin insertion into a metal-alkyl bond and olefin metathesis and a clos
Reptin and Pontin oligomerization and activity are modulated through histone H3 N-terminal tail interaction.
Queval R, Papin C, Dalvai M, Bystricky K, Humbert O. Queval R, et al. J Biol Chem. 2014 Dec 5;289(49):33999-4012. doi: 10.1074/jbc.M114.576785. Epub 2014 Oct 21. J Biol Chem. 2014. PMID: 25336637 Free PMC article.
We propose that changes in the oligomeric status of Reptin/Pontin create a platform that brings specific cofactors close to gene promoters and loads regulatory factors to establish an active state of chromatin....
We propose that changes in the oligomeric status of Reptin/Pontin create a platform that brings specific cofactors close to gene prom …
In-depth characterization of bacterial and archaeal communities present in the abandoned Kettara pyrrhotite mine tailings (Morocco).
Bruneel O, Mghazli N, Hakkou R, Dahmani I, Filali Maltouf A, Sbabou L. Bruneel O, et al. Extremophiles. 2017 Jul;21(4):671-685. doi: 10.1007/s00792-017-0933-3. Epub 2017 Apr 26. Extremophiles. 2017. PMID: 28447266 Free article.
In Morocco, pollution caused by closed mines continues to be a serious threat to the environment, like the generation of acid mine drainage. ...
In Morocco, pollution caused by closed mines continues to be a serious threat to the environment, like the generation of acid mine dr …
Rhizobium alamii sp. nov., an exopolysaccharide-producing species isolated from legume and non-legume rhizospheres.
Berge O, Lodhi A, Brandelet G, Santaella C, Roncato MA, Christen R, Heulin T, Achouak W. Berge O, et al. Int J Syst Evol Microbiol. 2009 Feb;59(Pt 2):367-72. doi: 10.1099/ijs.0.000521-0. Int J Syst Evol Microbiol. 2009. PMID: 19196780
The genetic diversity revealed by REP-PCR fingerprinting indicated that the isolates correspond to different strains. 16S rRNA gene sequence analysis showed that the isolates are closely related to the strains Rhizobium sp. YAS34 and USDA 1920, respectively isolated from s …
The genetic diversity revealed by REP-PCR fingerprinting indicated that the isolates correspond to different strains. 16S rRNA gene sequence …
14 results