Noriyuki Yamaotsu - Search Results

Year	Number of Results
2004	3
2005	3
2006	1
2008	3
2009	3
2010	3
2011	3
2012	2
2013	2
2014	5
2015	2
2016	2
2017	6
2018	4
2019	2
2021	1
2022	1
2024	0

1

Synthesis and Evaluation of Habiterpenol Analogs.

Konya M, Arima S, Lee D, Ohtawa M, Shimoyama K, Fukuda T, Uchida R, Tomoda H, Yamaotsu N, Tanaka N, Nagamitsu T. Konya M, et al. Among authors: yamaotsu n. Chem Pharm Bull (Tokyo). 2022;70(4):261-268. doi: 10.1248/cpb.c21-00993. Chem Pharm Bull (Tokyo). 2022. PMID: 35370202 Free article.

2

3D-pharmacophore identification for kappa-opioid agonists using ligand-based drug-design techniques.

Yamaotsu N, Hirono S. Yamaotsu N, et al. Top Curr Chem. 2011;299:277-307. doi: 10.1007/128_2010_84. Top Curr Chem. 2011. PMID: 21630511 Review.

3

Multi-step virtual screening to develop selective DYRK1A inhibitors.

Koyama T, Yamaotsu N, Nakagome I, Ozawa SI, Yoshida T, Hayakawa D, Hirono S. Koyama T, et al. Among authors: yamaotsu n. J Mol Graph Model. 2017 Mar;72:229-239. doi: 10.1016/j.jmgm.2017.01.014. Epub 2017 Jan 15. J Mol Graph Model. 2017. PMID: 28129593

4

Structure-based virtual screening for novel chymase inhibitors by in silico fragment mapping.

Ozawa SI, Takahashi M, Yamaotsu N, Hirono S. Ozawa SI, et al. Among authors: yamaotsu n. J Mol Graph Model. 2019 Jun;89:102-108. doi: 10.1016/j.jmgm.2019.03.011. Epub 2019 Mar 12. J Mol Graph Model. 2019. PMID: 30884446

5

Identification of novel EED-EZH2 PPI inhibitors using an in silico fragment mapping method.

Misawa K, Yamaotsu N, Hirono S. Misawa K, et al. Among authors: yamaotsu n. J Comput Aided Mol Des. 2021 May;35(5):601-611. doi: 10.1007/s10822-021-00378-6. Epub 2021 Feb 26. J Comput Aided Mol Des. 2021. PMID: 33635506

6

Validation of molecular force field parameters for peptides including isomerized amino acids.

Oda A, Nakayoshi T, Fukuyoshi S, Kurimoto E, Yamaotsu N, Hirono S, Takahashi O. Oda A, et al. Among authors: yamaotsu n. Chirality. 2018 Apr;30(4):332-341. doi: 10.1002/chir.22821. Epub 2018 Feb 2. Chirality. 2018. PMID: 29393985

7

In silico fragment-mapping method: a new tool for fragment-based/structure-based drug discovery.

Yamaotsu N, Hirono S. Yamaotsu N, et al. J Comput Aided Mol Des. 2018 Nov;32(11):1229-1245. doi: 10.1007/s10822-018-0160-8. Epub 2018 Sep 8. J Comput Aided Mol Des. 2018. PMID: 30196523

8

In silico analyses of the effects of a point mutation and a pharmacological chaperone on the thermal fluctuation of phenylalanine hydroxylase.

Hayakawa D, Yamaotsu N, Nakagome I, Ozawa SI, Yoshida T, Hirono S. Hayakawa D, et al. Among authors: yamaotsu n. Biophys Chem. 2017 Sep;228:47-54. doi: 10.1016/j.bpc.2017.06.014. Epub 2017 Jun 30. Biophys Chem. 2017. PMID: 28697448

9

Three-dimensional quantitative structure-activity relationship analysis of inhibitors of human and rat cytochrome P4503A enzymes.

Handa K, Nakagome I, Yamaotsu N, Gouda H, Hirono S. Handa K, et al. Among authors: yamaotsu n. Drug Metab Pharmacokinet. 2013;28(4):345-55. doi: 10.2133/dmpk.dmpk-12-rg-133. Epub 2013 Jan 29. Drug Metab Pharmacokinet. 2013. PMID: 23358262 Free article.

10

Synthesis of a novel universal opioid receptor agonist with the 1,3,5-trioxazatriquinane skeleton and its pharmacologies.

Hirayama S, Wada N, Kuroda N, Iwai T, Yamaotsu N, Hirono S, Fujii H, Nagase H. Hirayama S, et al. Among authors: yamaotsu n. Bioorg Med Chem Lett. 2014 Oct 15;24(20):4895-8. doi: 10.1016/j.bmcl.2014.08.012. Epub 2014 Aug 12. Bioorg Med Chem Lett. 2014. PMID: 25248680

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