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An herbal medicine orengedokuto prevents indomethacin-induced enteropathy.
Miura N, Fukutake M, Yamamoto M, Ohtake N, Iizuka S, Imamura S, Tsuchiya N, Ishimatsu M, Nakamura Y, Ishige A, Watanabe K, Kase Y, Takeda S. Miura N, et al. Among authors: ohtake n. Biol Pharm Bull. 2007 Mar;30(3):495-501. doi: 10.1248/bpb.30.495. Biol Pharm Bull. 2007. PMID: 17329845 Free article.
3-Monoglucuronyl-glycyrrhretinic acid is a substrate of organic anion transporters expressed in tubular epithelial cells and plays important roles in licorice-induced pseudoaldosteronism by inhibiting 11β-hydroxysteroid dehydrogenase 2.
Makino T, Okajima K, Uebayashi R, Ohtake N, Inoue K, Mizukami H. Makino T, et al. Among authors: ohtake n. J Pharmacol Exp Ther. 2012 Aug;342(2):297-304. doi: 10.1124/jpet.111.190009. Epub 2012 Apr 27. J Pharmacol Exp Ther. 2012. PMID: 22543032
Inchinkoto, a herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.
Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y, Suzuki H. Okada K, et al. Among authors: ohtake n. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1450-63. doi: 10.1152/ajpgi.00302.2006. Epub 2006 Oct 12. Am J Physiol Gastrointest Liver Physiol. 2007. PMID: 17038627 Free article.
12 results