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Page 1
Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Andersen MK, Skotte L, Jørsboe E, Polito R, Stæger FF, Aldiss P, Hanghøj K, Waples RK, Santander CG, Grarup N, Dahl-Petersen IK, Diaz LJ, Overvad M, Senftleber NK, Søborg B, Larsen CVL, Lemoine C, Pedersen O, Feenstra B, Bjerregaard P, Melbye M, Jørgensen ME, Færgeman NJ, Koch A, Moritz T, Gillum MP, Moltke I, Hansen T, Albrechtsen A. Andersen MK, et al. Among authors: senftleber nk. Gastroenterology. 2022 Apr;162(4):1171-1182.e3. doi: 10.1053/j.gastro.2021.12.236. Epub 2021 Dec 13. Gastroenterology. 2022. PMID: 34914943 Free article.
An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention.
Jørsboe E, Andersen MK, Skotte L, Stæger FF, Færgeman NJ, Hanghøj K, Santander CG, Senftleber NK, Diaz LJ, Overvad M, Waples RK, Geller F, Bjerregaard P, Melbye M, Larsen CVL, Feenstra B, Anders Koch, Jørgensen ME, Grarup N, Moltke I, Albrechtsen A, Hansen T. Jørsboe E, et al. Among authors: senftleber nk. HGG Adv. 2022 Jun 9;3(4):100118. doi: 10.1016/j.xhgg.2022.100118. eCollection 2022 Oct 13. HGG Adv. 2022. PMID: 36267056 Free PMC article.
The effect of sucrase-isomaltase deficiency on metabolism, food intake and preferences: protocol for a dietary intervention study.
Senftleber NK, Skøtt Pedersen K, Schnoor Jørgensen C, Pedersen H, Bjerg Christensen MM, Kabel Madsen E, Andersen K, Jørsboe E, Gillum MP, Frøst MB, Hansen T, Jørgensen ME. Senftleber NK, et al. Int J Circumpolar Health. 2023 Dec;82(1):2178067. doi: 10.1080/22423982.2023.2178067. Epub 2023 Feb 22. Int J Circumpolar Health. 2023. PMID: 38113483 Free PMC article.
GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal.
Senftleber NK, Andersen MK, Jørsboe E, Stæger FF, Nøhr AK, Garcia-Erill G, Meisner J, Santander CG, Balboa RF, Gilly A, Bjerregaard P, Larsen CVL, Grarup N, Jørgensen ME, Zeggini E, Moltke I, Hansen T, Albrechtsen A. Senftleber NK, et al. Eur J Hum Genet. 2024 Feb;32(2):215-223. doi: 10.1038/s41431-023-01485-8. Epub 2023 Oct 30. Eur J Hum Genet. 2024. PMID: 37903942 Free PMC article.