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CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits.
Koornneef A, Vanshylla K, Hardenberg G, Rutten L, Strokappe NM, Tolboom J, Vreugdenhil J, Boer KF, Perkasa A, Blokland S, Burger JA, Huang WC, Lovell JF, van Manen D, Sanders RW, Zahn RC, Schuitemaker H, Langedijk JPM, Wegmann F. Koornneef A, et al. Among authors: strokappe nm. Nat Commun. 2024 Apr 11;15(1):3128. doi: 10.1038/s41467-024-47492-1. Nat Commun. 2024. PMID: 38605096 Free PMC article.
Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.
Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP Jr, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Martin L, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS, Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH. Barbian HJ, et al. Among authors: strokappe nm. mBio. 2015 Apr 21;6(2):e00296-15. doi: 10.1128/mBio.00296-15. mBio. 2015. PMID: 25900654 Free PMC article.
Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1.
McCoy LE, Rutten L, Frampton D, Anderson I, Granger L, Bashford-Rogers R, Dekkers G, Strokappe NM, Seaman MS, Koh W, Grippo V, Kliche A, Verrips T, Kellam P, Fassati A, Weiss RA. McCoy LE, et al. Among authors: strokappe nm. PLoS Pathog. 2014 Dec 18;10(12):e1004552. doi: 10.1371/journal.ppat.1004552. eCollection 2014 Dec. PLoS Pathog. 2014. PMID: 25522326 Free PMC article.
Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization.
McCoy LE, Quigley AF, Strokappe NM, Bulmer-Thomas B, Seaman MS, Mortier D, Rutten L, Chander N, Edwards CJ, Ketteler R, Davis D, Verrips T, Weiss RA. McCoy LE, et al. Among authors: strokappe nm. J Exp Med. 2012 Jun 4;209(6):1091-103. doi: 10.1084/jem.20112655. Epub 2012 May 28. J Exp Med. 2012. PMID: 22641382 Free PMC article.
A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 for neutralization but not for antigen recognition.
Lutje Hulsik D, Liu YY, Strokappe NM, Battella S, El Khattabi M, McCoy LE, Sabin C, Hinz A, Hock M, Macheboeuf P, Bonvin AM, Langedijk JP, Davis D, Forsman Quigley A, Aasa-Chapman MM, Seaman MS, Ramos A, Poignard P, Favier A, Simorre JP, Weiss RA, Verrips CT, Weissenhorn W, Rutten L. Lutje Hulsik D, et al. Among authors: strokappe nm. PLoS Pathog. 2013 Mar;9(3):e1003202. doi: 10.1371/journal.ppat.1003202. Epub 2013 Mar 7. PLoS Pathog. 2013. PMID: 23505368 Free PMC article.