Rethinking the clinical utility of distortion-product otoacoustic emission (DPOAE) signal-to-noise ratio

Int J Audiol. 2023 Jun 2:1-9. doi: 10.1080/14992027.2023.2215943. Online ahead of print.

Abstract

Objective: Distortion-product otoacoustic emission (DPOAE) levels are repeatable over time in normal-hearing individuals making DPOAE levels an ideal measurement for monitoring cochlear status in clinic and research applications. However, if DPOAE signal-to-noise ratio (SNR) values instead of levels are used for monitoring, the repeatability of this value needs to be established. This retrospective, cross-sectional study sought to determine DPOAE SNR repeatability in younger children, older children, young adults and a patient population with normal hearing.

Design: Each participant attended four sessions where DPOAE discrete frequency sweeps were collected at conventional (≤ 8 kHz) and/or extended-high frequencies (> 8 kHz). To examine the extent of variability to be expected for DPOAE SNR, average absolute SNR differences-between-trials were determined and compared to average absolute DPOAE level differences-between-trials.

Study samples: One hundred forty-five participants, incorporating four different groups from three different studies. Ages ranged from 3 to 55 years.

Results: Average SNR differences-between-trials across all frequencies are greater than differences for average DPOAE levels. Improved calibration methods result in SNR differences-between-trials that are similar across all frequencies.

Conclusions: When monitoring cochlear health over an extended bandwidth, DPOAE levels are less variable across trials than SNR values, thus allowing earlier indicators of cochlear damage.

Keywords: Otoacoustic emissions; calibration; distortion product otoacoustic emissions; monitoring; normal hearing; signal-to-noise ratio.