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Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy.
Luczak ED, Wu Y, Granger JM, Joiner MA, Wilson NR, Gupta A, Umapathi P, Murphy KR, Reyes Gaido OE, Sabet A, Corradini E, Tseng WW, Wang Y, Heck AJR, Wei AC, Weiss RG, Anderson ME. Luczak ED, et al. Among authors: wilson nr. Nat Commun. 2020 Sep 4;11(1):4416. doi: 10.1038/s41467-020-18165-6. Nat Commun. 2020. PMID: 32887881 Free PMC article.
Inhibition of MCU forces extramitochondrial adaptations governing physiological and pathological stress responses in heart.
Rasmussen TP, Wu Y, Joiner ML, Koval OM, Wilson NR, Luczak ED, Wang Q, Chen B, Gao Z, Zhu Z, Wagner BA, Soto J, McCormick ML, Kutschke W, Weiss RM, Yu L, Boudreau RL, Abel ED, Zhan F, Spitz DR, Buettner GR, Song LS, Zingman LV, Anderson ME. Rasmussen TP, et al. Among authors: wilson nr. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):9129-34. doi: 10.1073/pnas.1504705112. Epub 2015 Jul 7. Proc Natl Acad Sci U S A. 2015. PMID: 26153425 Free PMC article.