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Page 1
Introduction: Drug Resistance.
Kurt Yilmaz N, Schiffer CA. Kurt Yilmaz N, et al. Chem Rev. 2021 Mar 24;121(6):3235-3237. doi: 10.1021/acs.chemrev.1c00118. Chem Rev. 2021. PMID: 33757288 Free PMC article. No abstract available.
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Boby ML, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson MC; COVID Moonshot Consortium‡; Chodera JD, Lee AA, London N, von Delft A, von Delft F, Achdout H, Aimon A, Alonzi DS, Arbon R, Aschenbrenner JC, Balcomb BH, Bar-David E, Barr H, Ben-Shmuel A, Bennett J, Bilenko VA, Borden B, Boulet P, Bowman GR, Brewitz L, Brun J, Bvnbs S, Calmiano M, Carbery A, Carney DW, Cattermole E, Chang E, Chernyshenko E, Clyde A, Coffland JE, Cohen G, Cole JC, Contini A, Cox L, Croll TI, Cvitkovic M, De Jonghe S, Dias A, Donckers K, Dotson DL, Douangamath A, Duberstein S, Dudgeon T, Dunnett LE, Eastman P, Erez N, Eyermann CJ, Fairhead M, Fate G, Fedorov O, Fernandes RS, Ferrins L, Foster R, Foster H, Fraisse L, Gabizon R, García-Sastre A, Gawriljuk VO, Gehrtz P, Gileadi C, Giroud C, Glass WG, Glen RC, Glinert I, Godoy AS, Gorichko M, Gorrie-Stone T, Griffen EJ, Haneef A, Hassell Hart S, Heer J, Henry M, Hill M, Horrell S, Huang QYJ, Huliak VD, Hurley MFD, Israely T, Jajack A, Jansen J, Jnoff E, Jochmans D, John T, Kaminow B, Kang L, Kantsadi AL, Kenny PW, Kiappes JL, Kinakh SO, Kovar B, Krojer T, La VNT, Laghnimi-Hahn S, Lefker BA, Levy H, Lithgo RM, Logvinenko IG, Lukacik P, Macdonald HB, MacLean … See abstract for full author list ➔ Boby ML, et al. Among authors: yilmaz nk. Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10. Science. 2023. PMID: 37943932 Free PMC article.
Improving Viral Protease Inhibitors to Counter Drug Resistance.
Kurt Yilmaz N, Swanstrom R, Schiffer CA. Kurt Yilmaz N, et al. Trends Microbiol. 2016 Jul;24(7):547-557. doi: 10.1016/j.tim.2016.03.010. Epub 2016 Apr 15. Trends Microbiol. 2016. PMID: 27090931 Free PMC article. Review.
Viral proteases: Structure, mechanism and inhibition.
Zephyr J, Kurt Yilmaz N, Schiffer CA. Zephyr J, et al. Among authors: kurt yilmaz n. Enzymes. 2021;50:301-333. doi: 10.1016/bs.enz.2021.09.004. Epub 2021 Nov 17. Enzymes. 2021. PMID: 34861941 Free PMC article.
Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.
Matthew AN, Leidner F, Lockbaum GJ, Henes M, Zephyr J, Hou S, Rao DN, Timm J, Rusere LN, Ragland DA, Paulsen JL, Prachanronarong K, Soumana DI, Nalivaika EA, Kurt Yilmaz N, Ali A, Schiffer CA. Matthew AN, et al. Among authors: kurt yilmaz n. Chem Rev. 2021 Mar 24;121(6):3238-3270. doi: 10.1021/acs.chemrev.0c00648. Epub 2021 Jan 7. Chem Rev. 2021. PMID: 33410674 Free PMC article. Review.
Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease.
Zephyr J, Rao DN, Johnson C, Shaqra AM, Nalivaika EA, Jordan A, Kurt Yilmaz N, Ali A, Schiffer CA. Zephyr J, et al. Among authors: kurt yilmaz n. Bioorg Chem. 2023 Feb;131:106269. doi: 10.1016/j.bioorg.2022.106269. Epub 2022 Nov 19. Bioorg Chem. 2023. PMID: 36446201 Free PMC article.
Inhibiting HTLV-1 Protease: A Viable Antiviral Target.
Lockbaum GJ, Henes M, Talledge N, Rusere LN, Kosovrasti K, Nalivaika EA, Somasundaran M, Ali A, Mansky LM, Kurt Yilmaz N, Schiffer CA. Lockbaum GJ, et al. Among authors: kurt yilmaz n. ACS Chem Biol. 2021 Mar 19;16(3):529-538. doi: 10.1021/acschembio.0c00975. Epub 2021 Feb 23. ACS Chem Biol. 2021. PMID: 33619959 Free PMC article.
72 results