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ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis.
Farrawell NE, Bax M, McAlary L, McKenna J, Maksour S, Do-Ha D, Rayner SL, Blair IP, Chung RS, Yerbury JJ, Ooi L, Saunders DN. Farrawell NE, et al. Hum Mol Genet. 2023 Jul 4;32(14):2386-2398. doi: 10.1093/hmg/ddad063. Hum Mol Genet. 2023. PMID: 37220877 Free PMC article.
TDP-43 is a ubiquitylation substrate of the SCFcyclin F complex.
Rayner SL, Yang S, Farrawell NE, Jagaraj CJ, Cheng F, Davidson JM, Luu L, Redondo AG, Rábano A, Borrego-Hernández D, Atkin JD, Morsch M, Blair IP, Yerbury JJ, Chung R, Lee A. Rayner SL, et al. Among authors: farrawell ne. Neurobiol Dis. 2022 Jun 1;167:105673. doi: 10.1016/j.nbd.2022.105673. Epub 2022 Feb 26. Neurobiol Dis. 2022. PMID: 35231559 Free article.
Flow cytometric measurement of the cellular propagation of TDP-43 aggregation.
Zeineddine R, Whiten DR, Farrawell NE, McAlary L, Hanspal MA, Kumita JR, Wilson MR, Yerbury JJ. Zeineddine R, et al. Among authors: farrawell ne. Prion. 2017 May 4;11(3):195-204. doi: 10.1080/19336896.2017.1314426. Epub 2017 May 9. Prion. 2017. PMID: 28486039 Free PMC article.
Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS.
Farrawell NE, McAlary L, Lum JS, Chisholm CG, Warraich ST, Blair IP, Vine KL, Saunders DN, Yerbury JJ. Farrawell NE, et al. iScience. 2020 Oct 20;23(11):101700. doi: 10.1016/j.isci.2020.101700. eCollection 2020 Nov 20. iScience. 2020. PMID: 33196025 Free PMC article.
16 results