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Page 1
Broken by the Cut: A Journey into the Role of Topoisomerase II in DNA Fragility.
Genes (Basel). 2019 Oct 12;10(10):791. doi: 10.3390/genes10100791.
Genes (Basel). 2019.
PMID: 31614754
Free PMC article.
Review.
Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis.
Michel N, Young HMR, Atkin ND, Arshad U, Al-Humadi R, Singh S, Manukyan A, Gore L, Burbulis IE, Wang YH, McConnell MJ.
Michel N, et al. Among authors: atkin nd.
Sci Rep. 2022 Jul 15;12(1):12156. doi: 10.1038/s41598-022-16516-5.
Sci Rep. 2022.
PMID: 35840793
Free PMC article.
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Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human.
Szlachta K, Thys RG, Atkin ND, Pierce LCT, Bekiranov S, Wang YH.
Szlachta K, et al. Among authors: atkin nd.
Genome Biol. 2018 Jul 12;19(1):89. doi: 10.1186/s13059-018-1463-8.
Genome Biol. 2018.
PMID: 30001206
Free PMC article.
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DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity.
Raimer Young HM, Hou PC, Bartosik AR, Atkin ND, Wang L, Wang Z, Ratan A, Zang C, Wang YH.
Raimer Young HM, et al. Among authors: atkin nd.
Nucleic Acids Res. 2024 Apr 24;52(7):3837-3855. doi: 10.1093/nar/gkae164.
Nucleic Acids Res. 2024.
PMID: 38452213
Free PMC article.
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Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.
Atkin ND, Raimer HM, Wang Z, Zang C, Wang YH.
Atkin ND, et al.
Genes Chromosomes Cancer. 2021 Dec;60(12):808-821. doi: 10.1002/gcc.22993. Epub 2021 Aug 26.
Genes Chromosomes Cancer. 2021.
PMID: 34405474
Free PMC article.
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