Qualitative behaviour of a stochastic hepatitis C epidemic model in cellular level

Math Biosci Eng. 2022 Jan;19(2):1515-1535. doi: 10.3934/mbe.2022070. Epub 2021 Dec 8.

Abstract

In this paper, a mathematical model describing the dynamical of the spread of hepatitis C virus (HCV) at a cellular level with a stochastic noise in the transmission rate is developed from the deterministic model. The unique time-global solution for any positive initial value is served. The Ito's Formula, the suitable Lyapunov function, and other stochastic analysis techniques are used to analyze the model dynamics. The numerical simulations are carried out to describe the analytical results. These results highlight the impact of the noise intensity accelerating the extinction of the disease.

Keywords: extinction; hepatitis C virus; numerical simulation; persistence in mean; stochastic noise; transmission rate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Simulation
  • Hepacivirus*
  • Hepatitis C* / epidemiology
  • Humans
  • Models, Biological
  • Stochastic Processes