Human Purkinje cells outperform mouse Purkinje cells in dendritic complexity and computational capacity.
Masoli S, Sanchez-Ponce D, Vrieler N, Abu-Haya K, Lerner V, Shahar T, Nedelescu H, Rizza MF, Benavides-Piccione R, DeFelipe J, Yarom Y, Munoz A, D'Angelo E.
Masoli S, et al.
Commun Biol. 2024 Jan 2;7(1):5. doi: 10.1038/s42003-023-05689-y.
Commun Biol. 2024.
PMID: 38168772
Free PMC article.
Intrinsic electro-responsiveness was similar between the two species, but model simulations revealed that the dendrites could process ~6.5 times (n = 51 vs. n = 8) more input patterns in human Purkinje cells than in mouse Purkinje cells. ...
Intrinsic electro-responsiveness was similar between the two species, but model simulations revealed that the dendrites could process ~6.5 t …