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ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia.
Maes T, Mascaró C, Tirapu I, Estiarte A, Ciceri F, Lunardi S, Guibourt N, Perdones A, Lufino MMP, Somervaille TCP, Wiseman DH, Duy C, Melnick A, Willekens C, Ortega A, Martinell M, Valls N, Kurz G, Fyfe M, Castro-Palomino JC, Buesa C. Maes T, et al. Among authors: valls n. Cancer Cell. 2018 Mar 12;33(3):495-511.e12. doi: 10.1016/j.ccell.2018.02.002. Epub 2018 Mar 1. Cancer Cell. 2018. PMID: 29502954 Free article.
Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations.
Maes T, Mascaró C, Rotllant D, Lufino MMP, Estiarte A, Guibourt N, Cavalcanti F, Griñan-Ferré C, Pallàs M, Nadal R, Armario A, Ferrer I, Ortega A, Valls N, Fyfe M, Martinell M, Castro Palomino JC, Buesa Arjol C. Maes T, et al. Among authors: valls n. PLoS One. 2020 May 29;15(5):e0233468. doi: 10.1371/journal.pone.0233468. eCollection 2020. PLoS One. 2020. PMID: 32469975 Free PMC article.
DNA variability in five crystal structures of d(CGCAATTGCG).
Valls N, Wright G, Steiner RA, Murshudov GN, Subirana JA. Valls N, et al. Acta Crystallogr D Biol Crystallogr. 2004 Apr;60(Pt 4):680-5. doi: 10.1107/S0907444904002896. Epub 2004 Mar 23. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15039556 Free article.
Structure of a DNA duplex with all-AT base pairs.
Valls N, Richter M, Subirana JA. Valls N, et al. Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. doi: 10.1107/S0907444905029781. Epub 2005 Nov 19. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 16301792