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Multifaceted Bioanalytical Methods for the Comprehensive Pharmacokinetic and Catabolic Assessment of MEDI3726, an Anti-Prostate-Specific Membrane Antigen Pyrrolobenzodiazepine Antibody-Drug Conjugate.
Anal Chem. 2020 Aug 18;92(16):11135-11144. doi: 10.1021/acs.analchem.0c01187. Epub 2020 Jul 1.
Anal Chem. 2020.
PMID: 32459957
Free article.
Clinical Trial.
Immunoaffinity LC-MS/MS to quantify a PEGylated anti-Factor D Fab biotherapeutic in cynomolgus monkey serum.
Liu L, Liu Y, Dai L, Stella C, Faria M, Shao J, Hicks JL, Cortes DF, Mylott WR Jr, Wakshull E, Kaur S, Xu K.
Liu L, et al. Among authors: faria m.
Bioanalysis. 2019 Dec;11(23):2161-2173. doi: 10.4155/bio-2019-0082. Epub 2019 Nov 8.
Bioanalysis. 2019.
PMID: 31701759
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An extended stable isotope-labeled signature peptide internal standard for tracking immunocapture of human plasma osteopontin for LC-MS/MS quantification.
Faria M, Halquist MS, Yuan M, Mylott W Jr, Jenkins RG, Karnes HT.
Faria M, et al.
Biomed Chromatogr. 2015 Nov;29(11):1780-2. doi: 10.1002/bmc.3471. Epub 2015 Apr 27.
Biomed Chromatogr. 2015.
PMID: 25919310
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Multiplex LC-MS/MS Assays for Clinical Bioanalysis of MEDI4276, an Antibody-Drug Conjugate of Tubulysin Analogue Attached via Cleavable Linker to a Biparatopic Humanized Antibody against HER-2.
Faria M, Peay M, Lam B, Ma E, Yuan M, Waldron M, Mylott WR Jr, Liang M, Rosenbaum AI.
Faria M, et al.
Antibodies (Basel). 2019 Jan 11;8(1):11. doi: 10.3390/antib8010011.
Antibodies (Basel). 2019.
PMID: 31544817
Free PMC article.
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Comparison of a stable isotope labeled (SIL) peptide and an extended SIL peptide as internal standards to track digestion variability of an unstable signature peptide during quantification of a cancer biomarker, human osteopontin, from plasma using capillary microflow LC-MS/MS.
Faria M, Halquist MS, Yuan M, Mylott W Jr, Jenkins RG, Karnes HT.
Faria M, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Sep 15;1001:156-68. doi: 10.1016/j.jchromb.2015.05.040. Epub 2015 Jul 26.
J Chromatogr B Analyt Technol Biomed Life Sci. 2015.
PMID: 26279007
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Liquid chromatography-tandem mass spectrometry method for quantification of thymidine kinase activity in human serum by monitoring the conversion of 3'-deoxy-3'-fluorothymidine to 3'-deoxy-3'-fluorothymidine monophosphate.
Faria M, Halquist MS, Kindt E, Li W, Karnes HT, O'Brien PJ.
Faria M, et al.
J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 15;907:13-20. doi: 10.1016/j.jchromb.2012.08.024. Epub 2012 Aug 24.
J Chromatogr B Analyt Technol Biomed Life Sci. 2012.
PMID: 22995377
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