A new five-parameter Birnbaum-Saunders distribution for modeling bicoid gene expression data

Math Biosci. 2020 Jan:319:108275. doi: 10.1016/j.mbs.2019.108275. Epub 2019 Nov 28.

Abstract

An extended version of Birnbaum-Saunders distribution with five parameters is introduced. Theoretical aspects of five-parameter Birnbaum-Saunders distribution and the maximum likelihood estimation of parameters are presented. The reliability and applicability of the proposed distribution is evaluated using both simulation and real-world data namely bicoid gene expression profile. The findings of this research confirm that the newly proposed five-parameter Birnbaum-Saunders distribution can be utilized to describe the distribution of bicoid gene expression profile.

Keywords: Bicoid gene; Birnbaum–Saunders distribution; Gene expression profile; Maximum likelihood estimation.

MeSH terms

  • Computer Simulation
  • Gene Expression*
  • Humans
  • Models, Genetic*
  • Models, Statistical*