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Showing results for miri
Your search for Mirig retrieved no results
HIF‑1α in myocardial ischemia‑reperfusion injury (Review).
Zheng J, Chen P, Zhong J, Cheng Y, Chen H, He Y, Chen C. Zheng J, et al. Mol Med Rep. 2021 May;23(5):352. doi: 10.3892/mmr.2021.11991. Epub 2021 Mar 24. Mol Med Rep. 2021. PMID: 33760122 Free PMC article. Review.
Myocardial ischemia-reperfusion injury (MIRI) is a severe injury to the ischemic myocardium following the recovery of blood flow. ...The present review summarizes the roles and associated mechanisms of action of HIF-1alpha in MIRI. In addition, HIF-1alpha-associated …
Myocardial ischemia-reperfusion injury (MIRI) is a severe injury to the ischemic myocardium following the recovery of blood flow. ... …
Ferroptosis: Opportunities and Challenges in Myocardial Ischemia-Reperfusion Injury.
Zhao WK, Zhou Y, Xu TT, Wu Q. Zhao WK, et al. Oxid Med Cell Longev. 2021 Oct 23;2021:9929687. doi: 10.1155/2021/9929687. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34725566 Free PMC article. Review.
Ferroptosis is mainly characterized by mitochondrial shrinkage, increased density of bilayer membranes, and the accumulation of lipid peroxidation. Myocardial ischemia-reperfusion injury (MIRI) is an unavoidable risk event for acute myocardial infarction. Ferroptosis is cl …
Ferroptosis is mainly characterized by mitochondrial shrinkage, increased density of bilayer membranes, and the accumulation of lipid peroxi …
Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management (Review).
He J, Liu D, Zhao L, Zhou D, Rong J, Zhang L, Xia Z. He J, et al. Exp Ther Med. 2022 Jun;23(6):430. doi: 10.3892/etm.2022.11357. Epub 2022 May 6. Exp Ther Med. 2022. PMID: 35607376 Free PMC article. Review.
However, when the interrupted myocardial blood supply is recovered within a certain period of time, it causes more serious damage to the original ischemic myocardium; this is known as myocardial ischemia/reperfusion injury (MIRI). The pathophysiological mechanisms leading …
However, when the interrupted myocardial blood supply is recovered within a certain period of time, it causes more serious damage to the ori …
Relationship between ferroptosis and mitophagy in cardiac ischemia reperfusion injury: a mini-review.
Liu C, Li Z, Li B, Liu W, Zhang S, Qiu K, Zhu W. Liu C, et al. PeerJ. 2023 Mar 13;11:e14952. doi: 10.7717/peerj.14952. eCollection 2023. PeerJ. 2023. PMID: 36935924 Free PMC article. Review.
However, reperfusion therapy can lead to myocardial ischemia reperfusion injury (MIRI), which can affect the prognosis of patients. Studying the mechanisms of MIRI can help us improve the treatment of MIRI. The pathological process of MIRI involves man …
However, reperfusion therapy can lead to myocardial ischemia reperfusion injury (MIRI), which can affect the prognosis of patients. S …
CircHECTD1 promoted MIRI-associated inflammation via inhibiting miR-138-5p and upregulating ROCK2.
Yang YN, Luo YB, Xu G, Li K, Ma RL, Yuan W. Yang YN, et al. Kaohsiung J Med Sci. 2023 Jul;39(7):675-687. doi: 10.1002/kjm2.12686. Epub 2023 Apr 25. Kaohsiung J Med Sci. 2023. PMID: 37096660 Free article.
Inflammation and apoptosis were critical determinants during MIRI. We conveyed experiments to reveal the regulatory functions of circHECTD1 in MIRI development. The Rat MIRI model was established and determined by 2,3,5-triphenyl tetrazolium chloride (TTC) st …
Inflammation and apoptosis were critical determinants during MIRI. We conveyed experiments to reveal the regulatory functions of circ …
Propofol relieves inflammation in MIRI rats by inhibiting Rho/Rock signaling pathway.
Liu C, Li Y. Liu C, et al. Eur Rev Med Pharmacol Sci. 2021 Jan;25(2):976-984. doi: 10.26355/eurrev_202101_24667. Eur Rev Med Pharmacol Sci. 2021. PMID: 33577053 Free article.
All rats were divided into three groups, including sham operation group (Sham operation), MIRI group and MIRI + propofol group. At 2 h after reperfusion, myocardial tissues and blood samples were collected from rats. ...RESULTS: (1) The expression levels of serum LD …
All rats were divided into three groups, including sham operation group (Sham operation), MIRI group and MIRI + propofol group …
Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis via MAPK signaling inhibition.
Chen W, Zhang Y, Wang Z, Tan M, Lin J, Qian X, Li H, Jiang T. Chen W, et al. Front Pharmacol. 2023 Feb 20;14:1078205. doi: 10.3389/fphar.2023.1078205. eCollection 2023. Front Pharmacol. 2023. PMID: 36891270 Free PMC article.
Here, we investigated the effect and potential mechanism of DAPA against myocardial ischemia/reperfusion injury (MIRI)-related ferroptosis using the MIRI rat model and hypoxia/reoxygenation (H/R)-induced H9C2 cardiomyocytes. ...Subsequently, network pharmacology and …
Here, we investigated the effect and potential mechanism of DAPA against myocardial ischemia/reperfusion injury (MIRI)-related ferrop …
Small-Sized Cationic miRi-PCNPs Selectively Target the Kidneys for High-Efficiency Antifibrosis Treatment.
Geng X, Zhang M, Lai X, Tan L, Liu J, Yu M, Deng X, Hu J, Li A. Geng X, et al. Adv Healthc Mater. 2018 Nov;7(21):e1800558. doi: 10.1002/adhm.201800558. Epub 2018 Sep 12. Adv Healthc Mater. 2018. PMID: 30277665
In the miRi-PCNPs, easily degraded miRi is encapsulated in PCNPs and thus prevented from degradation by nuclease. ...For example, the tubule damage index and tubulointerstitial fibrosis area in the miRi-PCNPs group are 2.5-fold lower than those in the saline …
In the miRi-PCNPs, easily degraded miRi is encapsulated in PCNPs and thus prevented from degradation by nuclease. ...For examp …
Ginsenoside Rb1 Inhibits Cardiomyocyte Autophagy via PI3K/Akt/mTOR Signaling Pathway and Reduces Myocardial Ischemia/Reperfusion Injury.
Qin GW, Lu P, Peng L, Jiang W. Qin GW, et al. Am J Chin Med. 2021;49(8):1913-1927. doi: 10.1142/S0192415X21500907. Epub 2021 Nov 13. Am J Chin Med. 2021. PMID: 34775933
Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage in acute myocardial infarction, and its treatment remains a clinical challenge. ...Here, we found that Ginsenoside Rb1 treatment not only alleviated MIRI in rats but also prot …
Myocardial ischemia/reperfusion injury (MIRI) is the major cause of myocardial cell damage in acute myocardial infarction, and its tr …
2,416 results