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Development of a Molecular Blood-Based Immune Signature Classifier as Biomarker for Risks Assessment in Lung Cancer Screening.
Fortunato O, Huber V, Segale M, Cova A, Vallacchi V, Squarcina P, Rivoltini L, Suatoni P, Sozzi G, Pastorino U, Boeri M. Fortunato O, et al. Among authors: segale m. Cancer Epidemiol Biomarkers Prev. 2022 Nov 2;31(11):2020-2029. doi: 10.1158/1055-9965.EPI-22-0689. Cancer Epidemiol Biomarkers Prev. 2022. PMID: 36112827 Free PMC article.
Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling.
Di Paolo D, Pontis F, Moro M, Centonze G, Bertolini G, Milione M, Mensah M, Segale M, Petraroia I, Borzi C, Suatoni P, Brignole C, Perri P, Ponzoni M, Pastorino U, Sozzi G, Fortunato O. Di Paolo D, et al. Among authors: segale m. Mol Oncol. 2021 Nov;15(11):2969-2988. doi: 10.1002/1878-0261.13036. Epub 2021 Jul 21. Mol Oncol. 2021. PMID: 34107168 Free PMC article.
Age-Related Alterations in Immune Contexture Are Associated with Aggressiveness in Rhabdomyosarcoma.
Gasparini P, Fortunato O, De Cecco L, Casanova M, Iannó MF, Carenzo A, Centonze G, Milione M, Collini P, Boeri M, Dugo M, Gargiuli C, Mensah M, Segale M, Bergamaschi L, Chiaravalli S, Sensi ML, Massimino M, Sozzi G, Ferrari A. Gasparini P, et al. Among authors: segale m. Cancers (Basel). 2019 Sep 17;11(9):1380. doi: 10.3390/cancers11091380. Cancers (Basel). 2019. PMID: 31533233 Free PMC article.
Circulating extracellular vesicles from individuals at high-risk of lung cancer induce pro-tumorigenic conversion of stromal cells through transfer of miR-126 and miR-320.
Pontis F, Roz L, Mensah M, Segale M, Moro M, Bertolini G, Petraroia I, Centonze G, Ferretti AM, Suatoni P, Pastorino U, Fortunato O, Sozzi G. Pontis F, et al. Among authors: segale m. J Exp Clin Cancer Res. 2021 Jul 21;40(1):237. doi: 10.1186/s13046-021-02040-3. J Exp Clin Cancer Res. 2021. PMID: 34289890 Free PMC article.