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Vitamin E-inspired multi-scale imaging agent.
Ghelfi M, Maddalena LA, Stuart JA, Atkinson J, Harroun TA, Marquardt D. Ghelfi M, et al. Bioorg Med Chem Lett. 2019 Jan 1;29(1):107-114. doi: 10.1016/j.bmcl.2018.10.052. Epub 2018 Nov 2. Bioorg Med Chem Lett. 2019. PMID: 30459096
Vitamin E sequestration by liver fat in humans.
Violet PC, Ebenuwa IC, Wang Y, Niyyati M, Padayatty SJ, Head B, Wilkins K, Chung S, Thakur V, Ulatowski L, Atkinson J, Ghelfi M, Smith S, Tu H, Bobe G, Liu CY, Herion DW, Shamburek RD, Manor D, Traber MG, Levine M. Violet PC, et al. Among authors: ghelfi m. JCI Insight. 2020 Jan 16;5(1):e133309. doi: 10.1172/jci.insight.133309. JCI Insight. 2020. PMID: 31821172 Free PMC article. Clinical Trial.
The mitochondria-targeted imidazole substituted oleic acid 'TPP-IOA' affects mitochondrial bioenergetics and its protective efficacy in cells is influenced by cellular dependence on aerobic metabolism.
Maddalena LA, Ghelfi M, Atkinson J, Stuart JA. Maddalena LA, et al. Among authors: ghelfi m. Biochim Biophys Acta Bioenerg. 2017 Jan;1858(1):73-85. doi: 10.1016/j.bbabio.2016.11.005. Epub 2016 Nov 9. Biochim Biophys Acta Bioenerg. 2017. PMID: 27836699 Free article.