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AICAR inhibits ceramide biosynthesis in skeletal muscle.
Erickson KA, Smith ME, Anthonymuthu TS, Evanson MJ, Brassfield ES, Hodson AE, Bressler MA, Tucker BJ, Thatcher MO, Prince JT, Hancock CR, Bikman BT. Erickson KA, et al. Among authors: thatcher mo. Diabetol Metab Syndr. 2012 Nov 7;4(1):45. doi: 10.1186/1758-5996-4-45. Diabetol Metab Syndr. 2012. PMID: 23134616 Free PMC article.
Ceramides mediate cigarette smoke-induced metabolic disruption in mice.
Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT. Thatcher MO, et al. Am J Physiol Endocrinol Metab. 2014 Nov 15;307(10):E919-27. doi: 10.1152/ajpendo.00258.2014. Epub 2014 Sep 30. Am J Physiol Endocrinol Metab. 2014. PMID: 25269485 Free article.