Accurate and Efficient Intracranial Hemorrhage Detection and Subtype Classification in 3D CT Scans with Convolutional and Long Short-Term Memory Neural Networks

Sensors (Basel). 2020 Oct 1;20(19):5611. doi: 10.3390/s20195611.

Abstract

In this paper, we present our system for the RSNA Intracranial Hemorrhage Detection challenge, which is based on the RSNA 2019 Brain CT Hemorrhage dataset. The proposed system is based on a lightweight deep neural network architecture composed of a convolutional neural network (CNN) that takes as input individual CT slices, and a Long Short-Term Memory (LSTM) network that takes as input multiple feature embeddings provided by the CNN. For efficient processing, we consider various feature selection methods to produce a subset of useful CNN features for the LSTM. Furthermore, we reduce the CT slices by a factor of 2×, which enables us to train the model faster. Even if our model is designed to balance speed and accuracy, we report a weighted mean log loss of 0.04989 on the final test set, which places us in the top 30 ranking (2%) from a total of 1345 participants. While our computing infrastructure does not allow it, processing CT slices at their original scale is likely to improve performance. In order to enable others to reproduce our results, we provide our code as open source. After the challenge, we conducted a subjective intracranial hemorrhage detection assessment by radiologists, indicating that the performance of our deep model is on par with that of doctors specialized in reading CT scans. Another contribution of our work is to integrate Grad-CAM visualizations in our system, providing useful explanations for its predictions. We therefore consider our system as a viable option when a fast diagnosis or a second opinion on intracranial hemorrhage detection are needed.

Keywords: convolutional neural networks; intracranial hemorrhage detection; intracranial hemorrhage subtype classification; long short-term memory networks.

MeSH terms

  • Humans
  • Intracranial Hemorrhages / diagnostic imaging*
  • Neural Networks, Computer*
  • Tomography, X-Ray Computed*