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PRC2-Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1-Targeted Therapy via Enhanced Viral Mimicry.
Patel AJ, Warda S, Maag JLV, Misra R, Miranda-Román MA, Pachai MR, Lee CJ, Li D, Wang N, Bayshtok G, Fishinevich E, Meng Y, Wong EWP, Yan J, Giff E, Pappalardi MB, McCabe MT, Fletcher JA, Rudin CM, Chandarlapaty S, Scandura JM, Koche RP, Glass JL, Antonescu CR, Zheng D, Chen Y, Chi P. Patel AJ, et al. Among authors: miranda roman ma. Cancer Discov. 2022 Sep 2;12(9):2120-2139. doi: 10.1158/2159-8290.CD-21-1671. Cancer Discov. 2022. PMID: 35789380 Free PMC article.
Targeting MicroRNA-143 Leads to Inhibition of Glioblastoma Tumor Progression.
Lozada-Delgado EL, Grafals-Ruiz N, Miranda-Román MA, Santana-Rivera Y, Valiyeva F, Rivera-Díaz M, Marcos-Martínez MJ, Vivas-Mejía PE. Lozada-Delgado EL, et al. Among authors: miranda roman ma. Cancers (Basel). 2018 Oct 12;10(10):382. doi: 10.3390/cancers10100382. Cancers (Basel). 2018. PMID: 30322013 Free PMC article.
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
Yan J, Chen Y, Patel AJ, Warda S, Lee CJ, Nixon BG, Wong EW, Miranda-Román MA, Yang N, Wang Y, Pachai MR, Sher J, Giff E, Tang F, Khurana E, Singer S, Liu Y, Galbo PM Jr, Maag JL, Koche RP, Zheng D, Antonescu CR, Deng L, Li MO, Chen Y, Chi P. Yan J, et al. Among authors: miranda roman ma. J Clin Invest. 2022 Sep 1;132(17):e153437. doi: 10.1172/JCI153437. J Clin Invest. 2022. PMID: 35852856 Free PMC article.
Extensive alterations of blood metabolites in pediatric cerebral malaria.
Gupta S, Seydel K, Miranda-Roman MA, Feintuch CM, Saidi A, Kim RS, Birbeck GL, Taylor T, Daily JP. Gupta S, et al. Among authors: miranda roman ma. PLoS One. 2017 Apr 20;12(4):e0175686. doi: 10.1371/journal.pone.0175686. eCollection 2017. PLoS One. 2017. PMID: 28426698 Free PMC article.