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2019 1
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Page 1
An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity.
Lemke C, Benýšek J, Brajtenbach D, Breuer C, Jílková A, Horn M, Buša M, Ulrychová L, Illies A, Kubatzky KF, Bartz U, Mareš M, Gütschow M. Lemke C, et al. Among authors: busa m. J Med Chem. 2021 Sep 23;64(18):13793-13806. doi: 10.1021/acs.jmedchem.1c01178. Epub 2021 Sep 2. J Med Chem. 2021. PMID: 34473502
The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin.
Kotál J, Stergiou N, Buša M, Chlastáková A, Beránková Z, Řezáčová P, Langhansová H, Schwarz A, Calvo E, Kopecký J, Mareš M, Schmitt E, Chmelař J, Kotsyfakis M. Kotál J, et al. Among authors: busa m. Cell Mol Life Sci. 2019 May;76(10):2003-2013. doi: 10.1007/s00018-019-03034-3. Epub 2019 Feb 12. Cell Mol Life Sci. 2019. PMID: 30747251
Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes.
Benýšek J, Buša M, Rubešová P, Fanfrlík J, Lepšík M, Brynda J, Matoušková Z, Bartz U, Horn M, Gütschow M, Mareš M. Benýšek J, et al. Among authors: busa m. J Enzyme Inhib Med Chem. 2022 Dec;37(1):515-526. doi: 10.1080/14756366.2021.2024527. J Enzyme Inhib Med Chem. 2022. PMID: 35144520 Free PMC article.
An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans.
Matoušková Z, Orsághová K, Srb P, Pytelková J, Kukačka Z, Buša M, Hajdušek O, Šíma R, Fábry M, Novák P, Horn M, Kopáček P, Mareš M. Matoušková Z, et al. Among authors: busa m. Int J Mol Sci. 2024 Feb 13;25(4):2240. doi: 10.3390/ijms25042240. Int J Mol Sci. 2024. PMID: 38396918 Free PMC article.