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Attenuation of peripheral serotonin inhibits tumor growth and enhances immune checkpoint blockade therapy in murine tumor models.
Schneider MA, Heeb L, Beffinger MM, Pantelyushin S, Linecker M, Roth L, Lehmann K, Ungethüm U, Kobold S, Graf R, van den Broek M, Vom Berg J, Gupta A, Clavien PA. Schneider MA, et al. Among authors: beffinger mm. Sci Transl Med. 2021 Sep 15;13(611):eabc8188. doi: 10.1126/scitranslmed.abc8188. Epub 2021 Sep 15. Sci Transl Med. 2021. PMID: 34524861
HDR-based CRISPR/Cas9-mediated Knockout of PD-L1 in C57BL/6 Mice.
Heeb LV, Taskoparan B, Katsoulas A, Beffinger M, Clavien PA, Kobold S, Gupta A, Berg JV. Heeb LV, et al. Among authors: beffinger m. Bio Protoc. 2023 Jul 20;13(14):e4724. doi: 10.21769/BioProtoc.4724. eCollection 2023 Jul 20. Bio Protoc. 2023. PMID: 37497456 Free PMC article.
CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis.
Beffinger M, Tallón de Lara P, Tugues S, Vermeer M, Montagnolo Y, Ohs I, Cecconi V, Lucchiari G, Gagliardi A, Misljencevic N, Sutton J, Spörri R, Becher B, Gupta A, van den Broek M. Beffinger M, et al. JCI Insight. 2018 May 17;3(10):e97792. doi: 10.1172/jci.insight.97792. eCollection 2018 May 17. JCI Insight. 2018. PMID: 29769439 Free PMC article.