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Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming.
Velez-Delgado A, Donahue KL, Brown KL, Du W, Irizarry-Negron V, Menjivar RE, Lasse Opsahl EL, Steele NG, The S, Lazarus J, Sirihorachai VR, Yan W, Kemp SB, Kerk SA, Bollampally M, Yang S, Scales MK, Avritt FR, Lima F, Lyssiotis CA, Rao A, Crawford HC, Bednar F, Frankel TL, Allen BL, Zhang Y, Pasca di Magliano M. Velez-Delgado A, et al. Among authors: scales mk. Cell Mol Gastroenterol Hepatol. 2022;13(6):1673-1699. doi: 10.1016/j.jcmgh.2022.02.016. Epub 2022 Mar 1. Cell Mol Gastroenterol Hepatol. 2022. PMID: 35245687 Free PMC article.
Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer.
Scales MK, Velez-Delgado A, Steele NG, Schrader HE, Stabnick AM, Yan W, Mercado Soto NM, Nwosu ZC, Johnson C, Zhang Y, Salas-Escabillas DJ, Menjivar RE, Maurer HC, Crawford HC, Bednar F, Olive KP, Pasca di Magliano M, Allen BL. Scales MK, et al. PLoS Genet. 2022 Jul 22;18(7):e1010315. doi: 10.1371/journal.pgen.1010315. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35867772 Free PMC article.
Differential Contribution of Pancreatic Fibroblast Subsets to the Pancreatic Cancer Stroma.
Garcia PE, Adoumie M, Kim EC, Zhang Y, Scales MK, El-Tawil YS, Shaikh AZ, Wen HJ, Bednar F, Allen BL, Wellik DM, Crawford HC, Pasca di Magliano M. Garcia PE, et al. Among authors: scales mk. Cell Mol Gastroenterol Hepatol. 2020;10(3):581-599. doi: 10.1016/j.jcmgh.2020.05.004. Epub 2020 May 23. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32454112 Free PMC article.
Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling.
Konopelski Snavely SE, Susman MW, Kunz RC, Tan J, Srinivasan S, Cohen MD, Okada K, Lamb H, Choi SS, Karuna EP, Scales MK, Gygi SP, Greenberg ME, Ho HH. Konopelski Snavely SE, et al. Among authors: scales mk. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2104944118. doi: 10.1073/pnas.2104944118. Proc Natl Acad Sci U S A. 2021. PMID: 34135125 Free PMC article.
Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.
Susman MW, Karuna EP, Kunz RC, Gujral TS, Cantú AV, Choi SS, Jong BY, Okada K, Scales MK, Hum J, Hu LS, Kirschner MW, Nishinakamura R, Yamada S, Laird DJ, Jao LE, Gygi SP, Greenberg ME, Ho HH. Susman MW, et al. Among authors: scales mk. Elife. 2017 Sep 8;6:e26509. doi: 10.7554/eLife.26509. Elife. 2017. PMID: 28885975 Free PMC article.