Single-shot Talbot-Lau x-ray dark-field imaging of a porcine lung applying the moiré imaging approach

Phys Med Biol. 2018 Sep 13;63(18):185010. doi: 10.1088/1361-6560/aadafe.

Abstract

Talbot-Lau x-ray imaging provides additionally to the conventional attenuation image, two further images: the differential phase-contrast image which is especially sensitive to differences in refractive properties and the dark-field image which is showing the x-ray scattering properties of the object. Thus, in the dark-field image sub-pixeled object information can be observed. As it has been shown in recent studies, this is of special interest for lung imaging. Changes in the alveoli structure, which are in the size of one detector pixel, can be seen in the dark-field images. A fast acquisition process is crucial to avoid motion artifacts due to heartbeat and breathing of the patient. Using moiré imaging the images can be acquired with a single-shot exposure. Nevertheless, the spatial resolution is reduced compared to the phase-stepping acquisition. We evaluate the results of both imaging techniques towards their feasibility in clinical routine. Furthermore, we analyse the influence of artificial linear object movement on the image quality, in order to simulate the heartbeat of a patient.

MeSH terms

  • Animals
  • Interferometry / instrumentation
  • Interferometry / methods*
  • Lung / diagnostic imaging*
  • Movement
  • Phantoms, Imaging*
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Radiography / instrumentation
  • Radiography / methods*
  • Swine
  • X-Rays