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A single intranasal administration of AdCOVID protects against SARS-CoV-2 infection in the upper and lower respiratory tracts.
Schultz MD, Suschak JJ, Botta D, Silva-Sanchez A, King RG, Detchemendy TW, Meshram CD, Foote JB, Zhou F, Tipper JL, Zhang J, Harrod KS, Leal SM Jr, Randall TD, Roberts MS, Georges B, Lund FE. Schultz MD, et al. Hum Vaccin Immunother. 2022 Nov 30;18(6):2127292. doi: 10.1080/21645515.2022.2127292. Epub 2022 Oct 4. Hum Vaccin Immunother. 2022. PMID: 36194255 Free PMC article.
Single-dose intranasal administration of AdCOVID elicits systemic and mucosal immunity against SARS-CoV-2 in mice.
King RG, Silva-Sanchez A, Peel JN, Botta D, Meza-Perez S, Allie R, Schultz MD, Liu M, Bradley JE, Qiu S, Yang G, Zhou F, Zumaquero E, Simpler TS, Mousseau B, Killian JT, Dean B, Shang Q, Tipper JL, Risley C, Harrod KS, Feng R, Lee Y, Shiberu B, Krishnan V, Peguillet I, Zhang J, Green T, Randall TD, Georges B, Lund FE, Roberts S. King RG, et al. Among authors: schultz md. bioRxiv [Preprint]. 2020 Oct 11:2020.10.10.331348. doi: 10.1101/2020.10.10.331348. bioRxiv. 2020. PMID: 33052351 Free PMC article. Updated. Preprint.
T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells.
Stone SL, Peel JN, Scharer CD, Risley CA, Chisolm DA, Schultz MD, Yu B, Ballesteros-Tato A, Wojciechowski W, Mousseau B, Misra RS, Hanidu A, Jiang H, Qi Z, Boss JM, Randall TD, Brodeur SR, Goldrath AW, Weinmann AS, Rosenberg AF, Lund FE. Stone SL, et al. Among authors: schultz md. Immunity. 2019 May 21;50(5):1172-1187.e7. doi: 10.1016/j.immuni.2019.04.004. Epub 2019 May 7. Immunity. 2019. PMID: 31076359 Free PMC article.
Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge.
King RG, Silva-Sanchez A, Peel JN, Botta D, Dickson AM, Pinto AK, Meza-Perez S, Allie SR, Schultz MD, Liu M, Bradley JE, Qiu S, Yang G, Zhou F, Zumaquero E, Simpler TS, Mousseau B, Killian JT Jr, Dean B, Shang Q, Tipper JL, Risley CA, Harrod KS, Feng T, Lee Y, Shiberu B, Krishnan V, Peguillet I, Zhang J, Green TJ, Randall TD, Suschak JJ, Georges B, Brien JD, Lund FE, Roberts MS. King RG, et al. Among authors: schultz md. Vaccines (Basel). 2021 Aug 9;9(8):881. doi: 10.3390/vaccines9080881. Vaccines (Basel). 2021. PMID: 34452006 Free PMC article.