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Showing results for michael closer
Search for Michael Cloer instead (1 results)
Gluten-Free Diet in Celiac Disease-Forever and for All?
Itzlinger A, Branchi F, Elli L, Schumann M. Itzlinger A, et al. Nutrients. 2018 Nov 18;10(11):1796. doi: 10.3390/nu10111796. Nutrients. 2018. PMID: 30453686 Free PMC article. Review.
The gluten-free diet is the only effective treatment available for celiac disease. However, it is difficult to adhere to and a closer look on the diet's implementation and indications reveals several ambiguities: Not only is there controversy on the threshold of gluten tha …
The gluten-free diet is the only effective treatment available for celiac disease. However, it is difficult to adhere to and a closer …
Inter-organ crosstalk during development and progression of type 2 diabetes mellitus.
Xourafa G, Korbmacher M, Roden M. Xourafa G, et al. Nat Rev Endocrinol. 2024 Jan;20(1):27-49. doi: 10.1038/s41574-023-00898-1. Epub 2023 Oct 16. Nat Rev Endocrinol. 2024. PMID: 37845351 Review.
While the role of endocrine dysregulation in T2DM pathogenesis is well established, other forms of inter-organ crosstalk deserve closer investigation to better understand the multifactorial transition from normoglycaemia to hyperglycaemia. ...
While the role of endocrine dysregulation in T2DM pathogenesis is well established, other forms of inter-organ crosstalk deserve closer …
Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors.
Ludford K, Ho WJ, Thomas JV, Raghav KPS, Murphy MB, Fleming ND, Lee MS, Smaglo BG, You YN, Tillman MM, Kamiya-Matsuoka C, Thirumurthi S, Messick C, Johnson B, Vilar E, Dasari A, Shin S, Hernandez A, Yuan X, Yang H, Foo WC, Qiao W, Maru D, Kopetz S, Overman MJ. Ludford K, et al. J Clin Oncol. 2023 Apr 20;41(12):2181-2190. doi: 10.1200/JCO.22.01351. Epub 2023 Jan 9. J Clin Oncol. 2023. PMID: 36623241 Free PMC article. Clinical Trial.
Spatial immune profiling with imaging mass cytometry noted a significantly closer proximity between granulocytic cells and cytotoxic T cells in patients with progressive events compared with those without progression. ...
Spatial immune profiling with imaging mass cytometry noted a significantly closer proximity between granulocytic cells and cytotoxic …
Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3.
Scher HI, Morris MJ, Stadler WM, Higano C, Basch E, Fizazi K, Antonarakis ES, Beer TM, Carducci MA, Chi KN, Corn PG, de Bono JS, Dreicer R, George DJ, Heath EI, Hussain M, Kelly WK, Liu G, Logothetis C, Nanus D, Stein MN, Rathkopf DE, Slovin SF, Ryan CJ, Sartor O, Small EJ, Smith MR, Sternberg CN, Taplin ME, Wilding G, Nelson PS, Schwartz LH, Halabi S, Kantoff PW, Armstrong AJ; Prostate Cancer Clinical Trials Working Group 3. Scher HI, et al. J Clin Oncol. 2016 Apr 20;34(12):1402-18. doi: 10.1200/JCO.2015.64.2702. Epub 2016 Feb 22. J Clin Oncol. 2016. PMID: 26903579 Free PMC article.
Serial biologic profiling using tumor samples from biopsies, blood-based diagnostics, and/or imaging is also recommended to gain insight into mechanisms of resistance and to identify predictive biomarkers of sensitivity for use in prospective trials. CONCLUSION: PCWG3 moves drug …
Serial biologic profiling using tumor samples from biopsies, blood-based diagnostics, and/or imaging is also recommended to gain insight int …
A look into retinal organoids: methods, analytical techniques, and applications.
Afanasyeva TAV, Corral-Serrano JC, Garanto A, Roepman R, Cheetham ME, Collin RWJ. Afanasyeva TAV, et al. Cell Mol Life Sci. 2021 Oct;78(19-20):6505-6532. doi: 10.1007/s00018-021-03917-4. Epub 2021 Aug 22. Cell Mol Life Sci. 2021. PMID: 34420069 Free PMC article. Review.
Finally, we will discuss the outlook for improvements that would bring the cellular model a step closer to become an established system in research and treatment development of IRDs....
Finally, we will discuss the outlook for improvements that would bring the cellular model a step closer to become an established syst …
Calcifediol: a review of its pharmacological characteristics and clinical use in correcting vitamin D deficiency.
Jodar E, Campusano C, de Jongh RT, Holick MF. Jodar E, et al. Eur J Nutr. 2023 Jun;62(4):1579-1597. doi: 10.1007/s00394-023-03103-1. Epub 2023 Mar 2. Eur J Nutr. 2023. PMID: 36862209 Free PMC article. Review.
It is independent of hepatic 25-hydroxylation and thus is one step closer in the metabolic pathway to active vitamin D. At comparable doses to vitamin D(3), calcifediol achieves target serum 25(OH)D concentrations more rapidly and in contrast to vitamin D(3), it has a pred …
It is independent of hepatic 25-hydroxylation and thus is one step closer in the metabolic pathway to active vitamin D. At comparable …
Interpolated Flaps.
Ramsey ML, Ellison CA, Hohman MH, Al Aboud AM. Ramsey ML, et al. 2024 Jan 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2024 Jan 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 29262248 Free Books & Documents.
After 4 to 6 weeks, the pedicle is released from the donor site, and the intermediate inset site then acts as the base of the flap as the end of the flap that was initially connected to the donor site is then moved either into the defect or a new intermediate inset site closer …
After 4 to 6 weeks, the pedicle is released from the donor site, and the intermediate inset site then acts as the base of the flap as the en …
Predicting benefit from immune checkpoint inhibitors in patients with non-small-cell lung cancer by CT-based ensemble deep learning: a retrospective study.
Saad MB, Hong L, Aminu M, Vokes NI, Chen P, Salehjahromi M, Qin K, Sujit SJ, Lu X, Young E, Al-Tashi Q, Qureshi R, Wu CC, Carter BW, Lin SH, Lee PP, Gandhi S, Chang JY, Li R, Gensheimer MF, Wakelee HA, Neal JW, Lee HS, Cheng C, Velcheti V, Lou Y, Petranovic M, Rinsurongkawong W, Le X, Rinsurongkawong V, Spelman A, Elamin YY, Negrao MV, Skoulidis F, Gay CM, Cascone T, Antonoff MB, Sepesi B, Lewis J, Wistuba II, Hazle JD, Chung C, Jaffray D, Gibbons DL, Vaporciyan A, Lee JJ, Heymach JV, Zhang J, Wu J. Saad MB, et al. Lancet Digit Health. 2023 Jul;5(7):e404-e420. doi: 10.1016/S2589-7500(23)00082-1. Epub 2023 May 31. Lancet Digit Health. 2023. PMID: 37268451 Free PMC article.
INTERPRETATION: This proof-of-concept study shows that automated profiling of radiographic scans through deep learning can provide orthogonal information independent of existing clinicopathological biomarkers, bringing the goal of precision immunotherapy for patients with NSCLC …
INTERPRETATION: This proof-of-concept study shows that automated profiling of radiographic scans through deep learning can provide orthogona …
283 results