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Modelling environmentally-mediated infectious diseases of humans: transmission dynamics of schistosomiasis in China.
Remais J. Remais J. Adv Exp Med Biol. 2010;673:79-98. doi: 10.1007/978-1-4419-6064-1_6. Adv Exp Med Biol. 2010. PMID: 20632531 Free PMC article. Review.
Macroparasites of humans are sensitive to a variety of environmental variables, including temperature, rainfall and hydrology, yet current comprehension of these relationships is limited. Given the incomplete mechanistic understanding of environment-disease interactions, m …
Macroparasites of humans are sensitive to a variety of environmental variables, including temperature, rainfall and hydrology, yet current c …
A simple method for determining compound affinity and chemical yield from DNA-encoded library selections.
Hall J, Foley TL, Chen Q, Israel DI, Xu Y, Ford KK, Xie P, Fan J, Wan J. Hall J, et al. Biochem Biophys Res Commun. 2020 Jun 18;527(1):250-256. doi: 10.1016/j.bbrc.2020.04.024. Epub 2020 May 4. Biochem Biophys Res Commun. 2020. PMID: 32446376
DNA-encoded libraries (DELs) can contain billions of unique chemical species; selecting against such large inputs, it is typical to find more candidate binders than is reasonable to pursue for follow-up synthesis and testing. Given this wealth of choices, common practice i …
DNA-encoded libraries (DELs) can contain billions of unique chemical species; selecting against such large inputs, it is typical to find mor …
Evaluation of post-introduction COVID-19 vaccine effectiveness: Summary of interim guidance of the World Health Organization.
Patel MK, Bergeri I, Bresee JS, Cowling BJ, Crowcroft NS, Fahmy K, Hirve S, Kang G, Katz MA, Lanata CF, L'Azou Jackson M, Joshi S, Lipsitch M, Mwenda JM, Nogareda F, Orenstein WA, Ortiz JR, Pebody R, Schrag SJ, Smith PG, Srikantiah P, Subissi L, Valenciano M, Vaughn DW, Verani JR, Wilder-Smith A, Feikin DR. Patel MK, et al. Vaccine. 2021 Jul 5;39(30):4013-4024. doi: 10.1016/j.vaccine.2021.05.099. Epub 2021 Jun 1. Vaccine. 2021. PMID: 34119350 Free PMC article.
Phase 3 randomized-controlled trials have provided promising results of COVID-19 vaccine efficacy, ranging from 50 to 95% against symptomatic disease as the primary endpoints, resulting in emergency use authorization/listing for several vaccines. However, given the short d …
Phase 3 randomized-controlled trials have provided promising results of COVID-19 vaccine efficacy, ranging from 50 to 95% against symptomati …
Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans.
Bahl J, Nelson MI, Chan KH, Chen R, Vijaykrishna D, Halpin RA, Stockwell TB, Lin X, Wentworth DE, Ghedin E, Guan Y, Peiris JS, Riley S, Rambaut A, Holmes EC, Smith GJ. Bahl J, et al. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19359-64. doi: 10.1073/pnas.1109314108. Epub 2011 Nov 14. Proc Natl Acad Sci U S A. 2011. PMID: 22084096 Free PMC article.
We therefore propose that the global persistence of H3N2 influenza A virus is the result of a migrating metapopulation in which multiple different localities may seed seasonal epidemics in temperate regions in a given year. Such complex global migration dynamics may confou …
We therefore propose that the global persistence of H3N2 influenza A virus is the result of a migrating metapopulation in which multiple dif …