Idiopathic Aneurysms of the Ascending Aorta in the Mouse and Rat.
Petkov D, Patrick DJ, Rogerson P, Rehagen D, Hennig G, Bradley A, Howroyd P, Czajkowski M, Decker J, Aboulmali A, Balmer B.
Petkov D, et al.
Toxicol Pathol. 2022 Jan;50(1):4-12. doi: 10.1177/01926233211056872. Epub 2021 Dec 2.
Toxicol Pathol. 2022.
PMID: 34855556
Aneurysms of the ascending aorta, unrelated to xenobiotic administration, are described in 5 rats and 2 mice in nonclinical safety studies conducted at Charles River Laboratories (CRL) sites over the past 10 years. The most prominent microscopic finding was focal dilation …
Aneurysms of the ascending aorta, unrelated to xenobiotic administration, are described in 5 rats and 2 mice in nonclinical safety studies c …