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DNA-methylation in C1R is a prognostic biomarker for acute myeloid leukemia.
Božić T, Lin Q, Frobel J, Wilop S, Hoffmann M, Müller-Tidow C, Brümmendorf TH, Jost E, Wagner W. Božić T, et al. Among authors: hoffmann m. Clin Epigenetics. 2015 Nov 4;7:116. doi: 10.1186/s13148-015-0153-6. eCollection 2015. Clin Epigenetics. 2015. PMID: 26539253 Free PMC article.
The SCLtTAxBCR-ABL transgenic mouse model closely reflects the differential effects of dasatinib on normal and malignant hematopoiesis in chronic phase-CML patients.
Schubert C, Chatain N, Braunschweig T, Schemionek M, Feldberg K, Hoffmann M, Dufva O, Mustjoki S, Brümmendorf TH, Koschmieder S. Schubert C, et al. Among authors: hoffmann m. Oncotarget. 2017 May 23;8(21):34736-34749. doi: 10.18632/oncotarget.16152. Oncotarget. 2017. PMID: 28423730 Free PMC article.