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Page 1
In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.
Int J Mol Sci. 2019 Nov 21;20(23):5854. doi: 10.3390/ijms20235854.
Int J Mol Sci. 2019.
PMID: 31766565
Free PMC article.
Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.
Arsović A, Halbach MV, Canet-Pons J, Esen-Sehir D, Döring C, Freudenberg F, Czechowska N, Seidel K, Baader SL, Gispert S, Sen NE, Auburger G.
Arsović A, et al. Among authors: halbach mv.
Int J Mol Sci. 2020 Sep 12;21(18):6673. doi: 10.3390/ijms21186673.
Int J Mol Sci. 2020.
PMID: 32932600
Free PMC article.
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Atxn2 Knockout and CAG42-Knock-in Cerebellum Shows Similarly Dysregulated Expression in Calcium Homeostasis Pathway.
Halbach MV, Gispert S, Stehning T, Damrath E, Walter M, Auburger G.
Halbach MV, et al.
Cerebellum. 2017 Feb;16(1):68-81. doi: 10.1007/s12311-016-0762-4.
Cerebellum. 2017.
PMID: 26868665
Free PMC article.
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Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.
Halbach MV, Stehning T, Damrath E, Jendrach M, Şen NE, Başak AN, Auburger G.
Halbach MV, et al.
PLoS One. 2015 Mar 19;10(3):e0121089. doi: 10.1371/journal.pone.0121089. eCollection 2015.
PLoS One. 2015.
PMID: 25790475
Free PMC article.
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