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Central Nervous System Outcomes of Lazertinib Versus Gefitinib in EGFR-Mutated Advanced NSCLC: A LASER301 Subset Analysis.
Soo RA, Cho BC, Kim JH, Ahn MJ, Lee KH, Zimina A, Orlov S, Bondarenko I, Lee YG, Lim YN, Lee SS, Lee KH, Pang YK, Fong CH, Kang JH, Lim CS, Danchaivijitr P, Kilickap S, Yang JC, Arslan C, Lee H, Park SN, Cicin I. Soo RA, et al. J Thorac Oncol. 2023 Dec;18(12):1756-1766. doi: 10.1016/j.jtho.2023.08.017. Epub 2023 Oct 22. J Thorac Oncol. 2023. PMID: 37865896 Free article. Clinical Trial.
RESULTS: Of the 393 patients enrolled in LASER301, 86 (lazertinib, n = 45; gefitinib, n = 41) had measurable and or non-measurable baseline CNS metastases. The median intracranial progression-free survival in the lazertinib group was 28.2 months (95% confidence interval [C …
RESULTS: Of the 393 patients enrolled in LASER301, 86 (lazertinib, n = 45; gefitinib, n = 41) had measurable and or non-measurable baseline …
Mobility and mortality outcomes among older individuals with hip fractures at a teaching hospital in Malaysia.
Khor HM, Tan MP, Kumar CS, Singh S, Tan KM, Saedon NB, Ong T, Chin AV, Kamaruzzaman SB, Hasmukharay K, Zakaria MIB, Teh HX, Tan FC, Chong PY. Khor HM, et al. Arch Osteoporos. 2022 Nov 30;17(1):151. doi: 10.1007/s11657-022-01183-w. Arch Osteoporos. 2022. PMID: 36447075
Of these, 284 patients (91.6%) underwent surgical intervention with a median time to surgery of 5 days (IQR 3-8) days. 60.4% of patients who underwent hip fracture surgery did not recover to their pre-fracture mobility status. ...
Of these, 284 patients (91.6%) underwent surgical intervention with a median time to surgery of 5 days (IQR 3-8) days. 60.4% of patie …
An investigation of geographical clusters of leptospirosis during the outbreak in Pangandaran, West Java, Indonesia.
Widawati M, Dhewantara PW, Anasi R, Wahono T, Marina R, Pertiwi IP, Wibowo AA, Ruliansyah A, Riandi MU, Widiastuti D, Astuti EP. Widawati M, et al. Geospat Health. 2023 Oct 5;18(2). doi: 10.4081/gh.2023.1221. Geospat Health. 2023. PMID: 37795863 Free article.
A total of 172 reported leptospirosis in 40 villages from 9 sub-districts in Pangandaran District were analysed. Of these, 132 cases (76.7%) were male. The median age was 49 years (interquartile range [IQR]: 34-59 years). ...Moran's I analysis showed significant spatial au …
A total of 172 reported leptospirosis in 40 villages from 9 sub-districts in Pangandaran District were analysed. Of these, 132 cases (76.7%) …
The quality of life and body image disturbances of Turner syndrome patients in Malaysia: a cross-sectional study.
Yusof AAB, Chii MLS, Yusoff NIM, Kama RNIFRM, Raj JR, Ghani NAA, Ali A, Syn JHS, Shah SA, Ishak NA, Akinyi AS, Zainuddin AA. Yusof AAB, et al. BMC Womens Health. 2023 Nov 17;23(1):614. doi: 10.1186/s12905-023-02745-x. BMC Womens Health. 2023. PMID: 37978374 Free PMC article.
RESULTS: A total of 34 TS patients were approached and 24 (70.5%) of them participated in this study. Their median (IQR) age was 24.0 (7.0) years and their responses were compared to 60 age-matched healthy females as controls [median age (IQR) = 24.0 (8.0) years]. . …
RESULTS: A total of 34 TS patients were approached and 24 (70.5%) of them participated in this study. Their median (IQR) age was 24.0 …
Impact of Lower-Limb Endurance Training on Dyspnea and Lung Functions in Patients with COPD.
Tarigan AP, Pandia P, Mutiara E, Pradana A, Rhinsilva E, Efriyandi E. Tarigan AP, et al. Open Access Maced J Med Sci. 2018 Dec 17;6(12):2354-2358. doi: 10.3889/oamjms.2018.381. eCollection 2018 Dec 20. Open Access Maced J Med Sci. 2018. PMID: 30607190 Free PMC article.
Patients' dyspnea scale also showed significant improvement (p < 0.001) from mMRC median scale 2 (range 1-3) to 1 (range 0-2) in both groups C and D. ...

Patients' dyspnea scale also showed significant improvement (p < 0.001) from mMRC median scale 2 (range 1-3) to 1 (range 0-2) in b

The enhanced recovery after surgery (ERAS) protocol implementation in a national tertiary-level hospital: a prospective cohort study.
Mazni Y, Syaiful RA, Ibrahim F, Jeo WS, Putranto AS, Sihardo L, Marbun V, Lalisang AN, Putranto R, Natadisastra RM, Sumariyono S, Nugroho AM, Manikam NRM, Karimah N, Hastuty V, Sutisna EN, Widiati E, Mutiara R, Wardhani RK, Liastuti LD, Lalisang TJM. Mazni Y, et al. Ann Med Surg (Lond). 2023 Dec 8;86(1):85-91. doi: 10.1097/MS9.0000000000001609. eCollection 2024 Jan. Ann Med Surg (Lond). 2023. PMID: 38222714 Free PMC article.
RESULTS: The length of stay in the ERAS group was shorter than the control group [median (interquartile range) 6 (5-7) vs. 13 (11-19), P<0.001], with a lower total cost of [USD 1875 (1234-3722) vs. ...
RESULTS: The length of stay in the ERAS group was shorter than the control group [median (interquartile range) 6 (5-7) vs. 13 (11-19) …