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Integrated radiogenomics analyses allow for subtype classification and improved outcome prognosis of patients with locally advanced HNSCC.
Rabasco Meneghetti A, Zwanenburg A, Linge A, Lohaus F, Grosser M, Baretton GB, Kalinauskaite G, Tinhofer I, Guberina M, Stuschke M, Balermpas P, von der Grün J, Ganswindt U, Belka C, Peeken JC, Combs SE, Böke S, Zips D, Troost EGC, Krause M, Baumann M, Löck S. Rabasco Meneghetti A, et al. Among authors: von der grun j. Sci Rep. 2022 Oct 6;12(1):16755. doi: 10.1038/s41598-022-21159-7. Sci Rep. 2022. PMID: 36202941 Free PMC article.
Dose-escalated re-irradiation improves outcome in locally recurrent head and neck cancer - Results of a large multicenter analysis.
Roesch J, Oertel M, Wegen S, Trommer M, Schleifenbaum J, Hering D, Mäurer M, Knippen S, Dobiasch S, Waltenberger M, von der Grün J, Medenwald D, Süß C, Hoeck M, Käsmann L, Fleischmann DF, Rühle A, Nicolay NH, Fabian A, Löser A, Heß S, Tamaskovics B, Vinsensia M, Hecht M; Young DEGRO Group. Roesch J, et al. Among authors: von der grun j. Radiother Oncol. 2023 Apr;181:109380. doi: 10.1016/j.radonc.2022.10.007. Epub 2022 Oct 20. Radiother Oncol. 2023. PMID: 36273736
Biomarker signatures for primary radiochemotherapy of locally advanced HNSCC - Hypothesis generation on a multicentre cohort of the DKTK-ROG.
Löck S, Linge A, Lohaus F, Ebert N, Gudziol V, Nowak A, Tinhofer I, Kalinauskaite G, Guberina M, Stuschke M, Balermpas P, von der Grün J, Grosu AL, Debus J, Ganswindt U, Belka C, Peeken JC, Combs SE, De-Colle C, Zips D, Baretton GB, Krause M, Baumann M; DKTK-ROG. Löck S, et al. Among authors: von der grun j. Radiother Oncol. 2022 Apr;169:8-14. doi: 10.1016/j.radonc.2022.02.009. Epub 2022 Feb 16. Radiother Oncol. 2022. PMID: 35182686
Integration of p16/HPV DNA Status with a 24-miRNA-Defined Molecular Phenotype Improves Clinically Relevant Stratification of Head and Neck Cancer Patients.
Hess J, Unger K, Maihoefer C, Schüttrumpf L, Weber P, Marschner S, Wintergerst L, Pflugradt U, Baumeister P, Walch A, Woischke C, Kirchner T, Werner M, Sörensen K, Baumann M, Tinhofer I, Combs SE, Debus J, Schäfer H, Krause M, Linge A, von der Grün J, Stuschke M, Zips D, Canis M, Lauber K, Ganswindt U, Henke M, Zitzelsberger H, Belka C. Hess J, et al. Among authors: von der grun j. Cancers (Basel). 2022 Jul 31;14(15):3745. doi: 10.3390/cancers14153745. Cancers (Basel). 2022. PMID: 35954409 Free PMC article.
Comprehensive Analysis of Tumour Sub-Volumes for Radiomic Risk Modelling in Locally Advanced HNSCC.
Leger S, Zwanenburg A, Leger K, Lohaus F, Linge A, Schreiber A, Kalinauskaite G, Tinhofer I, Guberina N, Guberina M, Balermpas P, von der Grün J, Ganswindt U, Belka C, Peeken JC, Combs SE, Boeke S, Zips D, Richter C, Krause M, Baumann M, Troost EGC, Löck S. Leger S, et al. Among authors: von der grun j. Cancers (Basel). 2020 Oct 19;12(10):3047. doi: 10.3390/cancers12103047. Cancers (Basel). 2020. PMID: 33086761 Free PMC article.
2D and 3D convolutional neural networks for outcome modelling of locally advanced head and neck squamous cell carcinoma.
Starke S, Leger S, Zwanenburg A, Leger K, Lohaus F, Linge A, Schreiber A, Kalinauskaite G, Tinhofer I, Guberina N, Guberina M, Balermpas P, von der Grün J, Ganswindt U, Belka C, Peeken JC, Combs SE, Boeke S, Zips D, Richter C, Troost EGC, Krause M, Baumann M, Löck S. Starke S, et al. Among authors: von der grun j. Sci Rep. 2020 Sep 24;10(1):15625. doi: 10.1038/s41598-020-70542-9. Sci Rep. 2020. PMID: 32973220 Free PMC article.
ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy.
Guberina M, Sak A, Pöttgen C, Tinhofer-Keilholz I, Budach V, Balermpas P, Von der Grün J, Rödel CM, Gkika E, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, De-Colle C, Welz S, Linge A, Lohaus F, Baretton G, Gauler T, Baumann M, Krause M, Schuler M, Bankfalvi A, Höing B, Lang S, Stuschke M. Guberina M, et al. Among authors: von der grun j. Pharmacogenomics J. 2021 Feb;21(1):37-46. doi: 10.1038/s41397-020-0174-1. Epub 2020 Jun 16. Pharmacogenomics J. 2021. PMID: 32546699 Free PMC article.
Interference of tumour mutational burden with outcome of patients with head and neck cancer treated with definitive chemoradiation: a multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group.
Eder T, Hess AK, Konschak R, Stromberger C, Jöhrens K, Fleischer V, Hummel M, Balermpas P, von der Grün J, Linge A, Lohaus F, Krause M, Baumann M, Stuschke M, Zips D, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Budach V, Tinhofer I; DKTK-ROG. Eder T, et al. Among authors: von der grun j. Eur J Cancer. 2019 Jul;116:67-76. doi: 10.1016/j.ejca.2019.04.015. Epub 2019 Jun 4. Eur J Cancer. 2019. PMID: 31173964
Correction: ERCC2 gene single-nucleotide polymorphism as a prognostic factor for locally advanced head and neck carcinomas after definitive cisplatin-based radiochemotherapy.
Guberina M, Sak A, Pöttgen C, Tinhofer-Keilholz I, Budach V, Balermpas P, Von der Grün J, Rödel CM, Gkika E, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, De-Colle C, Welz S, Linge A, Lohaus F, Baretton G, Gauler T, Baumann M, Krause M, Schuler M, Bankfalvi A, Höing B, Lang S, Stuschke M. Guberina M, et al. Among authors: von der grun j. Pharmacogenomics J. 2021 Apr;21(2):273. doi: 10.1038/s41397-020-00193-6. Pharmacogenomics J. 2021. PMID: 33009516 Free PMC article. No abstract available.