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Peppers: A "Hot" Natural Source for Antitumor Compounds.
Cunha MR, Tavares MT, Fernandes TB, Parise-Filho R. Cunha MR, et al. Among authors: tavares mt. Molecules. 2021 Mar 10;26(6):1521. doi: 10.3390/molecules26061521. Molecules. 2021. PMID: 33802144 Free PMC article. Review.
Structure-activity relationship and mechanistic studies for a series of cinnamyl hydroxamate histone deacetylase inhibitors.
Tavares MT, de Almeida LC, Kronenberger T, Monteiro Ferreira G, Fujii de Divitiis T, Franco Zannini Junqueira Toledo M, Mariko Aymoto Hassimotto N, Agostinho Machado-Neto J, Veras Costa-Lotufo L, Parise-Filho R. Tavares MT, et al. Bioorg Med Chem. 2021 Apr 1;35:116085. doi: 10.1016/j.bmc.2021.116085. Epub 2021 Feb 23. Bioorg Med Chem. 2021. PMID: 33668008
Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the cytoskeleton network.
Ferreira AK, de-Sá-Júnior PL, Pasqualoto KF, de Azevedo RA, Câmara DA, Costa AS, Figueiredo CR, Matsuo AL, Massaoka MH, Auada AV, Lebrun I, Damião MC, Tavares MT, Magri FM, Kerkis I, Parise Filho R. Ferreira AK, et al. Among authors: tavares mt. Biochimie. 2014 Apr;99:195-207. doi: 10.1016/j.biochi.2013.12.008. Epub 2013 Dec 16. Biochimie. 2014. PMID: 24355203
RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells.
de-Sá-Júnior PL, Pasqualoto KF, Ferreira AK, Tavares MT, Damião MC, de Azevedo RA, Câmara DA, Pereira A, de Souza DM, Parise Filho R. de-Sá-Júnior PL, et al. Among authors: tavares mt. Toxicol Appl Pharmacol. 2013 Feb 1;266(3):385-98. doi: 10.1016/j.taap.2012.11.029. Epub 2012 Dec 10. Toxicol Appl Pharmacol. 2013. PMID: 23238560
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