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GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Pairo-Castineira E, Rawlik K, Bretherick AD, Qi T, Wu Y, Nassiri I, McConkey GA, Zechner M, Klaric L, Griffiths F, Oosthuyzen W, Kousathanas A, Richmond A, Millar J, Russell CD, Malinauskas T, Thwaites R, Morrice K, Keating S, Maslove D, Nichol A, Semple MG, Knight J, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Begg C, Walsh T, Tenesa A, Flores C, Riancho JA, Rojas-Martinez A, Lapunzina P; GenOMICC Investigators; SCOURGE Consortium; ISARICC Investigators; 23andMe COVID-19 Team; Yang J, Ponting CP, Wilson JF, Vitart V, Abedalthagafi M, Luchessi AD, Parra EJ, Cruz R, Carracedo A, Fawkes A, Murphy L, Rowan K, Pereira AC, Law A, Fairfax B, Hendry SC, Baillie JK. Pairo-Castineira E, et al. Nature. 2023 May;617(7962):764-768. doi: 10.1038/s41586-023-06034-3. Epub 2023 May 17. Nature. 2023. PMID: 37198478 Free PMC article.
Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown(1) to be highly efficient for discovery of genetic associations(2). Despite the advanced stage of illness at presentation, we have shown that host genetics …
Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown(1) to be highly effici …
Non-contrast MRI methods as a tool for the pre-operative assessment and surveillance of the arterio-venous fistula for haemodialysis.
MacDonald CJ, Gandy S, Avison ECM, Matthew S, Ross R, Houston JG. MacDonald CJ, et al. Among authors: matthew s. MAGMA. 2018 Dec;31(6):735-745. doi: 10.1007/s10334-018-0700-1. Epub 2018 Aug 21. MAGMA. 2018. PMID: 30132298
OBJECTIVE: To compare non-contrast enhanced MRI with ultrasound (US) for measurement of arm blood vessel geometries and flow velocities in volunteers and patients with end-stage renal disease. MATERIALS AND METHODS: Subjects were scanned using US (reference standard), and …
OBJECTIVE: To compare non-contrast enhanced MRI with ultrasound (US) for measurement of arm blood vessel geometries and flow velocities in v …
The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database.
Vincent JL, Ferguson A, Pickkers P, Jakob SM, Jaschinski U, Almekhlafi GA, Leone M, Mokhtari M, Fontes LE, Bauer PR, Sakr Y; ICON Investigators. Vincent JL, et al. Crit Care. 2020 Apr 23;24(1):171. doi: 10.1186/s13054-020-02858-x. Crit Care. 2020. PMID: 32326981 Free PMC article.
BACKGROUND: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients …
BACKGROUND: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies …
Resilience of veterinarians at different career stages: The role of self-efficacy, coping strategies and personal resources for resilience in veterinary practice.
McArthur ML, Learey TJ, Jarden A, Van Gelderen I, Hazel SJ, Cake MA, Mansfield CF, Zaki S, Matthew SM. McArthur ML, et al. Among authors: matthew sm. Vet Rec. 2021 Dec;189(12):e771. doi: 10.1002/vetr.771. Epub 2021 Aug 23. Vet Rec. 2021. PMID: 34426964
METHOD: An online cross-sectional survey of 800 veterinarians collected demographic and descriptive data in two stages from late 2015 to 2017, such as gender, average hours worked per week, type and region of practice and intention to leave veterinary medicine. ...CONCLUSI …
METHOD: An online cross-sectional survey of 800 veterinarians collected demographic and descriptive data in two stages from late 2015 …
Development of convergent synaptic inputs to subpopulations of autonomic neurons.
Anderson RL, Jobling P, Matthew SE, Gibbins IL. Anderson RL, et al. Among authors: matthew se. J Comp Neurol. 2002 Jun 3;447(3):218-33. doi: 10.1002/cne.10222. J Comp Neurol. 2002. PMID: 11984817
Functional synaptogenesis occurred primarily from early fetal (F30-F35) to midfetal (F36-F45) stages, after the neurochemical differentiation of vasomotor and visceromotor neurons but before establishment of their electrophysiological phenotypes. ...However, the expression …
Functional synaptogenesis occurred primarily from early fetal (F30-F35) to midfetal (F36-F45) stages, after the neurochemical differe …