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213 results

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Showing results for matthew worse
Search for Matthew Worsey instead (3 results)
Targeting TREM2 on tumor-associated macrophages enhances immunotherapy.
Binnewies M, Pollack JL, Rudolph J, Dash S, Abushawish M, Lee T, Jahchan NS, Canaday P, Lu E, Norng M, Mankikar S, Liu VM, Du X, Chen A, Mehta R, Palmer R, Juric V, Liang L, Baker KP, Reyno L, Krummel MF, Streuli M, Sriram V. Binnewies M, et al. Cell Rep. 2021 Oct 19;37(3):109844. doi: 10.1016/j.celrep.2021.109844. Cell Rep. 2021. PMID: 34686340 Free article.
TREM2(+) TAMs are most enriched in individuals with ovarian cancer, where TREM2 expression corresponds to disease grade accompanied by worse recurrence-free survival. In an aggressive orthotopic ovarian cancer model, anti-TREM2 mAb therapy drives potent anti-tumor immunity …
TREM2(+) TAMs are most enriched in individuals with ovarian cancer, where TREM2 expression corresponds to disease grade accompanied by wo …
Microvascular stabilization via blood-brain barrier regulation prevents seizure activity.
Greene C, Hanley N, Reschke CR, Reddy A, Mäe MA, Connolly R, Behan C, O'Keeffe E, Bolger I, Hudson N, Delaney C, Farrell MA, O'Brien DF, Cryan J, Brett FM, Beausang A, Betsholtz C, Henshall DC, Doherty CP, Campbell M. Greene C, et al. Nat Commun. 2022 Apr 14;13(1):2003. doi: 10.1038/s41467-022-29657-y. Nat Commun. 2022. PMID: 35422069 Free PMC article.
Blood-brain barrier (BBB) dysfunction is associated with worse epilepsy outcomes however the underlying molecular mechanisms of BBB dysfunction remain to be elucidated. ...
Blood-brain barrier (BBB) dysfunction is associated with worse epilepsy outcomes however the underlying molecular mechanisms of BBB d …
The landscape of viral associations in human cancers.
Zapatka M, Borozan I, Brewer DS, Iskar M, Grundhoff A, Alawi M, Desai N, Sültmann H, Moch H; PCAWG Pathogens; Cooper CS, Eils R, Ferretti V, Lichter P; PCAWG Consortium. Zapatka M, et al. Nat Genet. 2020 Mar;52(3):320-330. doi: 10.1038/s41588-019-0558-9. Epub 2020 Feb 5. Nat Genet. 2020. PMID: 32025001 Free PMC article.
High levels of endogenous retrovirus (ERV1) expression were linked to a worse survival outcome in patients with kidney cancer....
High levels of endogenous retrovirus (ERV1) expression were linked to a worse survival outcome in patients with kidney cancer....
Radiation-induced circulating myeloid-derived suppressor cells induce systemic lymphopenia after chemoradiotherapy in patients with glioblastoma.
Ghosh S, Huang J, Inkman M, Zhang J, Thotala S, Tikhonova E, Miheecheva N, Frenkel F, Ataullakhanov R, Wang X, DeNardo D, Hallahan D, Thotala D. Ghosh S, et al. Sci Transl Med. 2023 Jan 25;15(680):eabn6758. doi: 10.1126/scitranslmed.abn6758. Epub 2023 Jan 25. Sci Transl Med. 2023. PMID: 36696484 Free PMC article.
Severe and prolonged lymphopenia frequently occurs in patients with glioblastoma after standard chemoradiotherapy and has been associated with worse survival, but its underlying biological mechanism is not well understood. ...
Severe and prolonged lymphopenia frequently occurs in patients with glioblastoma after standard chemoradiotherapy and has been associated wi …
Genetic Risk of Arrhythmic Phenotypes in Patients With Dilated Cardiomyopathy.
Gigli M, Merlo M, Graw SL, Barbati G, Rowland TJ, Slavov DB, Stolfo D, Haywood ME, Dal Ferro M, Altinier A, Ramani F, Brun F, Cocciolo A, Puggia I, Morea G, McKenna WJ, La Rosa FG, Taylor MRG, Sinagra G, Mestroni L. Gigli M, et al. J Am Coll Cardiol. 2019 Sep 17;74(11):1480-1490. doi: 10.1016/j.jacc.2019.06.072. J Am Coll Cardiol. 2019. PMID: 31514951 Free PMC article.
All-cause mortality was no different between variant carriers and noncarriers (p = 0.99). A trend toward worse SCD/VT/VF (p = 0.062) and DHF/HTx/VAD (p = 0.061) was found in carriers. ...
All-cause mortality was no different between variant carriers and noncarriers (p = 0.99). A trend toward worse SCD/VT/VF (p = 0.062) …
Autonomic Dysfunction.
Sánchez-Manso JC, Gujarathi R, Varacallo M. Sánchez-Manso JC, et al. 2023 Aug 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 28613638 Free Books & Documents.
Autonomic nervous system functions Dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a worse prognosis of the latter. In some circumstances or when severe, dysfunction of ANS itself results in symptoms and disability, which …
Autonomic nervous system functions Dysfunction of one or more subdivisions of the ANS, when accompanying other diseases, is linked to a w …
Acromioclavicular Joint Injection.
Merrigan B, Varacallo M. Merrigan B, et al. 2023 Aug 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Aug 4. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31613507 Free Books & Documents.
Patients with non-traumatic AC joint pain are usually older than 40 years of age and will typically present with focal shoulder pain located over the superior aspect of the shoulder. The pain is usually insidious and made worse with cross-body adduction of the shoulder. Pa …
Patients with non-traumatic AC joint pain are usually older than 40 years of age and will typically present with focal shoulder pain located …
Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial.
Smith MR, Scher HI, Sandhu S, Efstathiou E, Lara PN Jr, Yu EY, George DJ, Chi KN, Saad F, Ståhl O, Olmos D, Danila DC, Mason GE, Espina BM, Zhao X, Urtishak KA, Francis P, Lopez-Gitlitz A, Fizazi K; GALAHAD investigators. Smith MR, et al. Lancet Oncol. 2022 Mar;23(3):362-373. doi: 10.1016/S1470-2045(21)00757-9. Epub 2022 Feb 4. Lancet Oncol. 2022. PMID: 35131040 Free PMC article. Clinical Trial.
In the safety analysis population, the most common treatment-emergent adverse events of any grade were nausea (169 [58%] of 289), anaemia (156 [54%]), and vomiting (111 [38%]); the most common grade 3 or worse events were haematological (anaemia in 95 [33%] of 289; thrombo …
In the safety analysis population, the most common treatment-emergent adverse events of any grade were nausea (169 [58%] of 289), anaemia (1 …
Split-Thickness Skin Grafts.
Braza ME, Fahrenkopf MP. Braza ME, et al. 2023 Jul 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Jul 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31855388 Free Books & Documents.
Graft Take: The thicker a skin graft, the more metabolically active it is, and the worse is it's nutrient diffusion. FTSGs and thick STSG's require more robust recipient wound beds than thin STSGs. ...
Graft Take: The thicker a skin graft, the more metabolically active it is, and the worse is it's nutrient diffusion. FTSGs and thick …
A multi-country analysis of COVID-19 hospitalizations by vaccination status.
Gonçalves BP, Jassat W, Baruch J, Hashmi M, Rojek A, Dasgupta A, Martin-Loeches I, Reyes LF, Piubelli C, Citarella BW, Kartsonaki C, Lefèvre B, López Revilla JW, Lunn M, Harrison EM, Kraemer MUG, Shrapnel S, Horby P, Bisoffi Z, Olliaro PL, Merson L; ISARIC Clinical Characterisation Group. Gonçalves BP, et al. Med. 2023 Nov 10;4(11):797-812.e2. doi: 10.1016/j.medj.2023.08.005. Epub 2023 Sep 21. Med. 2023. PMID: 37738979 Free PMC article.
FINDINGS: While typical symptoms were more often reported in unvaccinated patients, comorbidities, including some associated with worse prognosis in previous studies, were more common in vaccinated patients. ...
FINDINGS: While typical symptoms were more often reported in unvaccinated patients, comorbidities, including some associated with worse …
213 results