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Page 1
An expanded universe of cancer targets.
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network. Hahn WC, et al. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Cell. 2021. PMID: 33667368 Free PMC article. Review.
DOT1L Is a Novel Cancer Stem Cell Target for Triple-Negative Breast Cancer.
Kurani H, Razavipour SF, Harikumar KB, Dunworth M, Ewald AJ, Nasir A, Pearson G, Van Booven D, Zhou Z, Azzam D, Wahlestedt C, Slingerland J. Kurani H, et al. Among authors: dunworth m. Clin Cancer Res. 2022 May 2;28(9):1948-1965. doi: 10.1158/1078-0432.CCR-21-1299. Clin Cancer Res. 2022. PMID: 35135840 Free PMC article.
Polyamine Homeostasis in Snyder-Robinson Syndrome.
Murray-Stewart T, Dunworth M, Foley JR, Schwartz CE, Casero RA Jr. Murray-Stewart T, et al. Among authors: dunworth m. Med Sci (Basel). 2018 Dec 7;6(4):112. doi: 10.3390/medsci6040112. Med Sci (Basel). 2018. PMID: 30544565 Free PMC article.
Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity.
Pope WH, Bowman CA, Russell DA, Jacobs-Sera D, Asai DJ, Cresawn SG, Jacobs WR, Hendrix RW, Lawrence JG, Hatfull GF; Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science; Phage Hunters Integrating Research and Education; Mycobacterial Genetics Course. Pope WH, et al. Elife. 2015 Apr 28;4:e06416. doi: 10.7554/eLife.06416. Elife. 2015. PMID: 25919952 Free PMC article.
Dual inhibitors of LSD1 and spermine oxidase.
Holshouser S, Dunworth M, Murray-Stewart T, Peterson YK, Burger P, Kirkpatrick J, Chen HH, Casero RA Jr, Woster PM. Holshouser S, et al. Among authors: dunworth m. Medchemcomm. 2019 Feb 8;10(5):778-790. doi: 10.1039/c8md00610e. eCollection 2019 May 1. Medchemcomm. 2019. PMID: 31191868 Free PMC article.
Cancer cells educate natural killer cells to a metastasis-promoting cell state.
Chan IS, Knútsdóttir H, Ramakrishnan G, Padmanaban V, Warrier M, Ramirez JC, Dunworth M, Zhang H, Jaffee EM, Bader JS, Ewald AJ. Chan IS, et al. Among authors: dunworth m. J Cell Biol. 2020 Sep 7;219(9):e202001134. doi: 10.1083/jcb.202001134. J Cell Biol. 2020. PMID: 32645139 Free PMC article.
A new class of cytotoxic agents targets tubulin and disrupts microtubule dynamics.
Al-Hamashi AA, Koranne R, Dlamini S, Alqahtani A, Karaj E, Rashid MS, Knoff JR, Dunworth M, Pflum MKH, Casero RA Jr, Perera L, Taylor WR, Tillekeratne LMV. Al-Hamashi AA, et al. Among authors: dunworth m. Bioorg Chem. 2021 Nov;116:105297. doi: 10.1016/j.bioorg.2021.105297. Epub 2021 Aug 30. Bioorg Chem. 2021. PMID: 34509798 Free PMC article.
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