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Identification and quantification of chain-pairing variants or mispaired species of asymmetric monovalent bispecific IgG1 monoclonal antibody format using reverse-phase polyphenyl chromatography coupled electrospray ionization mass spectrometry.
Poskute R, Sankaran PK, Sewell L, Lepore G, Shrubsall R, Dewis L, Watanabe Y, Wong V, Pascual Fernandez L, Mishra R, Holt A, Sou S, Harris C, Moreno Rodriguez C, Cankorur-Cetinkaya A, Smith J, Lonska N, Powell A, Cui T, Cheeks M, Lindo V. Poskute R, et al. Among authors: cheeks m. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Apr 15;1237:124085. doi: 10.1016/j.jchromb.2024.124085. Epub 2024 Mar 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2024. PMID: 38513430