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Year Number of Results
2014 2
2015 2
2016 2
2017 5
2018 4
2019 3
2020 2
2021 4
2022 3
2023 3
2024 1

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28 results

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Page 1
Repurposing of Drugs Targeting YAP-TEAD Functions.
Elisi GM, Santucci M, D'Arca D, Lauriola A, Marverti G, Losi L, Scalvini L, Bolognesi ML, Mor M, Costi MP. Elisi GM, et al. Among authors: santucci m. Cancers (Basel). 2018 Sep 14;10(9):329. doi: 10.3390/cancers10090329. Cancers (Basel). 2018. PMID: 30223434 Free PMC article. Review.
SCFβTrCP-mediated degradation of SHARP1 in triple-negative breast cancer.
Enriqué Steinberg JH, Rossi FA, Magliozzi R, Yuniati L, Santucci M, Rossi M, Guardavaccaro D, Lauriola A. Enriqué Steinberg JH, et al. Among authors: santucci m. Cell Death Dis. 2023 Nov 8;14(11):726. doi: 10.1038/s41419-023-06253-6. Cell Death Dis. 2023. PMID: 37938564 Free PMC article.
Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
Pöhner I, Quotadamo A, Panecka-Hofman J, Luciani R, Santucci M, Linciano P, Landi G, Di Pisa F, Dello Iacono L, Pozzi C, Mangani S, Gul S, Witt G, Ellinger B, Kuzikov M, Santarem N, Cordeiro-da-Silva A, Costi MP, Venturelli A, Wade RC. Pöhner I, et al. Among authors: santucci m. J Med Chem. 2022 Jul 14;65(13):9011-9033. doi: 10.1021/acs.jmedchem.2c00232. Epub 2022 Jun 8. J Med Chem. 2022. PMID: 35675511 Free PMC article.
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Costantino L, Ferrari S, Santucci M, Salo-Ahen OMH, Carosati E, Franchini S, Lauriola A, Pozzi C, Trande M, Gozzi G, Saxena P, Cannazza G, Losi L, Cardinale D, Venturelli A, Quotadamo A, Linciano P, Tagliazucchi L, Moschella MG, Guerrini R, Pacifico S, Luciani R, Genovese F, Henrich S, Alboni S, Santarem N, da Silva Cordeiro A, Giovannetti E, Peters GJ, Pinton P, Rimessi A, Cruciani G, Stroud RM, Wade RC, Mangani S, Marverti G, D'Arca D, Ponterini G, Costi MP. Costantino L, et al. Among authors: santucci m. Elife. 2022 Dec 7;11:e73862. doi: 10.7554/eLife.73862. Elife. 2022. PMID: 36475542 Free PMC article.
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents.
Linciano P, Quotadamo A, Luciani R, Santucci M, Zorn KM, Foil DH, Lane TR, Cordeiro da Silva A, Santarem N, B Moraes C, Freitas-Junior L, Wittig U, Mueller W, Tonelli M, Ferrari S, Venturelli A, Gul S, Kuzikov M, Ellinger B, Reinshagen J, Ekins S, Costi MP. Linciano P, et al. Among authors: santucci m. J Med Chem. 2023 Nov 23;66(22):15230-15255. doi: 10.1021/acs.jmedchem.3c01322. Epub 2023 Nov 3. J Med Chem. 2023. PMID: 37921561 Free PMC article.
Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting.
Marverti G, Marraccini C, Martello A, D'Arca D, Pacifico S, Guerrini R, Spyrakis F, Gozzi G, Lauriola A, Santucci M, Cannazza G, Tagliazucchi L, Cazzato AS, Losi L, Ferrari S, Ponterini G, Costi MP. Marverti G, et al. Among authors: santucci m. J Med Chem. 2021 Mar 25;64(6):3204-3221. doi: 10.1021/acs.jmedchem.0c02107. Epub 2021 Mar 12. J Med Chem. 2021. PMID: 33710891 Free PMC article.
The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents.
Linciano P, Pozzi C, Tassone G, Landi G, Mangani S, Santucci M, Luciani R, Ferrari S, Santarem N, Tagliazucchi L, Cordeiro-da-Silva A, Tonelli M, Tondi D, Bertarini L, Gul S, Witt G, Moraes CB, Costantino L, Costi MP. Linciano P, et al. Among authors: santucci m. Eur J Med Chem. 2024 Jan 15;264:115946. doi: 10.1016/j.ejmech.2023.115946. Epub 2023 Nov 11. Eur J Med Chem. 2024. PMID: 38043491
28 results