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Safety of cladribine tablets in the treatment of patients with multiple sclerosis: An integrated analysis.
Cook S, Leist T, Comi G, Montalban X, Giovannoni G, Nolting A, Hicking C, Galazka A, Sylvester E. Cook S, et al. Mult Scler Relat Disord. 2019 Apr;29:157-167. doi: 10.1016/j.msard.2018.11.021. Epub 2018 Nov 20. Mult Scler Relat Disord. 2019. PMID: 30885374 Free article.
In general there was no increase in the risk of infections including opportunistic infections with cladribine tablets versus placebo, except for herpes zoster. Periods of severe lymphopenia (< 0.5 10(9) cells/L) were associated with an increased frequency of infections, …
In general there was no increase in the risk of infections including opportunistic infections with cladribine tablets versus placebo, except …