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Showing results for margin luebke
Your search for Marvin Luepke retrieved no results
Nonredundant Upregulation of CD112R (PVRIG) and PD-1 on Cytotoxic T Lymphocytes Located in T Cell Nests of Colorectal Cancer.
Yang C, Mandelkow T, Bady E, Raedler JB, Simon R, Sauter G, Lennartz M, Büscheck F, Luebke AM, Dum D, Menz A, Höflmayer D, Weidemann S, Fraune C, Lebok P, Uhlig R, Bernreuther C, Jacobsen F, Clauditz TS, Wilczak W, Minner S, Burandt E, Steurer S, Blessin NC. Yang C, et al. Mod Pathol. 2023 Apr;36(4):100089. doi: 10.1016/j.modpat.2022.100089. Epub 2023 Jan 10. Mod Pathol. 2023. PMID: 36788088 Free article.
Although the highest mean CD112R expression on CD8(+) T cells was observed at the invasive margin, the PD-1 expression on CD8(+) T cells was elevated in the center of the tumor (P < .001 each). ...
Although the highest mean CD112R expression on CD8(+) T cells was observed at the invasive margin, the PD-1 expression on CD8(+) T ce …
Can homogeneous, lipomatous tumors be primarily resected without biopsy? A retrospective analysis of 240 tumors.
Ballhause TM, Weiss S, Reiter A, Frosch KH, Luebke AM, Bannas P, Schlickewei CW, Priemel MH. Ballhause TM, et al. World J Surg Oncol. 2022 Jun 8;20(1):184. doi: 10.1186/s12957-022-02665-4. World J Surg Oncol. 2022. PMID: 35676721 Free PMC article.
RESULTS: The collective comprised 142 tumors that were suspected as lipoma or ALT by the radiologist and underwent primary marginal resection (PMR). One case had myxoid liposarcoma that was underestimated on MRI and needed radical follow-up resection. ...Ninety-eight patie …
RESULTS: The collective comprised 142 tumors that were suspected as lipoma or ALT by the radiologist and underwent primary marginal r …
Immune Exclusion Is Frequent in Small-Cell Carcinoma of the Bladder.
Mandelkow T, Blessin NC, Lueerss E, Pott L, Simon R, Li W, Wellge B, Debatin NF, Höflmayer D, Izbicki JR, Büscheck F, Luebke AM, Wittmer C, Jacobsen F, Lutz F, Burandt E, Steurer S, Sauter G, Tsourlakis MC, Wilczak W, Hinsch A, Minner S. Mandelkow T, et al. Dis Markers. 2019 May 2;2019:2532518. doi: 10.1155/2019/2532518. eCollection 2019. Dis Markers. 2019. PMID: 31191745 Free PMC article.

In small-cell carcinomas, the average immune cell density in the CT (CD3: 159 206, CD8: 87 169 cells/mm(2)) was more than 3 times lower than that in the urothelial carcinomas (CD3: 625 800, p < 0.001; CD8: 362 626 cells/mm(2), p = 0.004) while there was no significant differen

In small-cell carcinomas, the average immune cell density in the CT (CD3: 159 206, CD8: 87 169 cells/mm(2)) was more than 3 times lower than …
Patterns of TIGIT Expression in Lymphatic Tissue, Inflammation, and Cancer.
Blessin NC, Simon R, Kluth M, Fischer K, Hube-Magg C, Li W, Makrypidi-Fraune G, Wellge B, Mandelkow T, Debatin NF, Höflmayer D, Lennartz M, Sauter G, Izbicki JR, Minner S, Büscheck F, Uhlig R, Dum D, Krech T, Luebke AM, Wittmer C, Jacobsen F, Burandt EC, Steurer S, Wilczak W, Hinsch A. Blessin NC, et al. Dis Markers. 2019 Jan 10;2019:5160565. doi: 10.1155/2019/5160565. eCollection 2019. Dis Markers. 2019. PMID: 30733837 Free PMC article.
TIGIT expression in tonsil gradually increased from the interfollicular area over the marginal/mantle zone to the germinal centre in all T cell subtypes. ...
TIGIT expression in tonsil gradually increased from the interfollicular area over the marginal/mantle zone to the germinal centre in …
Prevalence of proliferating CD8+ cells in normal lymphatic tissues, inflammation and cancer.
Blessin NC, Abu-Hashem R, Mandelkow T, Li W, Simon R, Hube-Magg C, Möller-Koop C, Witt M, Schmidt A, Büscheck F, Fraune C, Luebke AM, Möller K, Jacobsen F, Lutz F, Lennartz M, Steurer S, Sauter G, Höflmayer D, Tsourlakis MC, Hinsch A, Burandt E, Wilczak W, Minner S, Clauditz TS. Blessin NC, et al. Aging (Albany NY). 2021 Jun 3;13(11):14590-14603. doi: 10.18632/aging.203113. Epub 2021 Jun 3. Aging (Albany NY). 2021. PMID: 34083496 Free PMC article.
In cancers, the percentage of Ki67(+)CD8(+) cells was higher in the tumor center than at the invasive margin. In the tumor center of 765 colorectal cancers, the density of Ki67(+)CD8(+) cells and the percentage of proliferating CD8(+) cytotoxic T-cells was significantly as …
In cancers, the percentage of Ki67(+)CD8(+) cells was higher in the tumor center than at the invasive margin. In the tumor center of …
Loss of the adhesion molecule CEACAM1 is associated with early biochemical recurrence in TMPRSS2:ERG fusion-positive prostate cancers.
Luebke AM, Ricken W, Kluth M, Hube-Magg C, Schroeder C, Büscheck F, Möller K, Dum D, Höflmayer D, Weidemann S, Fraune C, Hinsch A, Wittmer C, Schlomm T, Huland H, Heinzer H, Graefen M, Haese A, Minner S, Simon R, Sauter G, Wilczak W, Meiners J. Luebke AM, et al. Int J Cancer. 2020 Jul 15;147(2):575-583. doi: 10.1002/ijc.32957. Epub 2020 Mar 18. Int J Cancer. 2020. PMID: 32150281 Free article.
Low and lost CEACAM1 expression was strongly linked to adverse tumor features including high classical and quantitative Gleason grade, lymph node metastasis, advanced tumor stage, positive surgical margin, a high number of genomic deletions and early biochemical recurrence …
Low and lost CEACAM1 expression was strongly linked to adverse tumor features including high classical and quantitative Gleason grade, lymph …
Upregulation of the transcription factor TFAP2D is associated with aggressive tumor phenotype in prostate cancer lacking the TMPRSS2:ERG fusion.
Fraune C, Harms L, Büscheck F, Höflmayer D, Tsourlakis MC, Clauditz TS, Simon R, Möller K, Luebke AM, Möller-Koop C, Steurer S, Hube-Magg C, Sauter G, Weidemann S, Lebok P, Dum D, Kind S, Minner S, Izbicki JR, Schlomm T, Huland H, Heinzer H, Burandt E, Haese A, Graefen M, Schroeder C. Fraune C, et al. Mol Med. 2020 Mar 6;26(1):24. doi: 10.1186/s10020-020-00148-4. Mol Med. 2020. PMID: 32143573 Free PMC article.
TFAP2D staining was significantly linked to advanced tumor stage, high classical and quantitative Gleason grade, lymph node metastasis, and a positive surgical margin (p 0.0045). TFAP2D positivity was more common in ERG fusion positive (88.7%) than in ERG negative cancers …
TFAP2D staining was significantly linked to advanced tumor stage, high classical and quantitative Gleason grade, lymph node metastasis, and …
13q deletion is linked to an adverse phenotype and poor prognosis in prostate cancer.
Kluth M, Scherzai S, Büschek F, Fraune C, Möller K, Höflmayer D, Minner S, Göbel C, Möller-Koop C, Hinsch A, Neubauer E, Tsourlakis MC, Sauter G, Heinzer H, Graefen M, Wilczak W, Luebke AM, Burandt E, Steurer S, Schlomm T, Simon R. Kluth M, et al. Genes Chromosomes Cancer. 2018 Oct;57(10):504-512. doi: 10.1002/gcc.22645. Epub 2018 Aug 20. Genes Chromosomes Cancer. 2018. PMID: 29923647

Deletions were always heterozygous and associated with high Gleason grade (P < .0001), advanced tumor stage (P < .0001), high preoperative prostate-specific antigen (PSA) levels (P = .0125), lymph node metastasis (P = .0377), positive resection margin (P = .0064), an

Deletions were always heterozygous and associated with high Gleason grade (P < .0001), advanced tumor stage (P < .0001), high preopera

Reduced KLK2 expression is a strong and independent predictor of poor prognosis in ERG-negative prostate cancer.
Bonk S, Kluth M, Jansen K, Hube-Magg C, Makrypidi-Fraune G, Höflmayer D, Weidemann S, Möller K, Uhlig R, Büscheck F, Luebke AM, Burandt E, Clauditz TS, Steurer S, Schlomm T, Huland H, Heinzer H, Sauter G, Simon R, Dum D. Bonk S, et al. Prostate. 2020 Sep;80(13):1097-1107. doi: 10.1002/pros.24038. Epub 2020 Jul 6. Prostate. 2020. PMID: 32628300

Lost or reduced KLK2 immunostaining was associated with advanced tumor stage, high Gleason score, lymph node metastasis, increased cell proliferation, positive resection margin, and early PSA recurrence (P < .0001). Comparison with previously analyzed molecular alterati

Lost or reduced KLK2 immunostaining was associated with advanced tumor stage, high Gleason score, lymph node metastasis, increased cell prol …
High CHK2 protein expression is a strong and independent prognostic feature in ERG negative prostate cancer.
Eichenauer T, Federlein F, Möller K, Chirico V, Kind S, Lennartz M, Lutz F, Hube-Magg C, Höflmayer D, Fisch M, Huland H, Heinzer H, Graefen M, Haese A, Schroeder C, Lebok P, Minner S, Simon R, Sauter G, Schlomm T, Wilczak W, Steurer S, Luebke AM. Eichenauer T, et al. Pathology. 2020 Jun;52(4):421-430. doi: 10.1016/j.pathol.2020.03.001. Epub 2020 Apr 18. Pathology. 2020. PMID: 32317175
Subgroup analysis of ERG positive and negative cancers revealed that high CHK2 staining was significantly linked to advanced tumour stage, high Gleason score, positive nodal status, positive surgical margin, high preoperative PSA (p<0.0001 each) and early prostate-speci …
Subgroup analysis of ERG positive and negative cancers revealed that high CHK2 staining was significantly linked to advanced tumour stage, h …
22 results