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IL-2-mediated hepatotoxicity: knowledge gap identification based on the irAOP concept.
Roser LA, Sakellariou C, Lindstedt M, Neuhaus V, Dehmel S, Sommer C, Raasch M, Flandre T, Roesener S, Hewitt P, Parnham MJ, Sewald K, Schiffmann S. Roser LA, et al. Among authors: raasch m. J Immunotoxicol. 2024 Dec;21(1):2332177. doi: 10.1080/1547691X.2024.2332177. Epub 2024 Apr 5. J Immunotoxicol. 2024. PMID: 38578203 Review.
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh CP, Guilet D, Troisi F, Neukirch K, König S, Bilancia R, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Roviezzo F, Sautebin L, Helesbeux JJ, Séraphin D, Mosig AS, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. Pein H, et al. Among authors: raasch m. Nat Commun. 2018 Sep 20;9(1):3834. doi: 10.1038/s41467-018-06158-5. Nat Commun. 2018. PMID: 30237488 Free PMC article.
A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies.
Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietzsche S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS. Maurer M, et al. Among authors: raasch m. Biomaterials. 2019 Nov;220:119396. doi: 10.1016/j.biomaterials.2019.119396. Epub 2019 Aug 2. Biomaterials. 2019. PMID: 31398556
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation.
Neukirch K, Alsabil K, Dinh CP, Bilancia R, Raasch M, Ville A, Cerqua I, Viault G, Bréard D, Pace S, Temml V, Brunner E, Jordan PM, Marques MC, Loeser K, Gollowitzer A, Permann S, Gerstmeier J, Lorkowski S, Stuppner H, Garscha U, Rodrigues T, Bernardes GJL, Schuster D, Séraphin D, Richomme P, Rossi A, Mosig AS, Roviezzo F, Werz O, Helesbeux JJ, Koeberle A. Neukirch K, et al. Among authors: raasch m. J Med Chem. 2021 Aug 12;64(15):11496-11526. doi: 10.1021/acs.jmedchem.1c00806. Epub 2021 Jul 19. J Med Chem. 2021. PMID: 34279935 Free PMC article.
16 results