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Development and validation of a hybrid immunoaffinity LC-MS/MS assay for quantitation of total antibody (TAb) from an antibody drug conjugate (ADC) PYX-201 in human plasma.
J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Aug 1;1228:123844. doi: 10.1016/j.jchromb.2023.123844. Epub 2023 Jul 26.
J Chromatogr B Analyt Technol Biomed Life Sci. 2023.
PMID: 37579604
Multifaceted Bioanalytical Methods for the Comprehensive Pharmacokinetic and Catabolic Assessment of MEDI3726, an Anti-Prostate-Specific Membrane Antigen Pyrrolobenzodiazepine Antibody-Drug Conjugate.
Huang Y, Del Nagro CJ, Balic K, Mylott WR Jr, Ismaiel OA, Ma E, Faria M, Wheeler AM, Yuan M, Waldron MP, Peay MG, Cortes DF, Roskos L, Liang M, Rosenbaum AI.
Huang Y, et al. Among authors: peay mg.
Anal Chem. 2020 Aug 18;92(16):11135-11144. doi: 10.1021/acs.analchem.0c01187. Epub 2020 Jul 1.
Anal Chem. 2020.
PMID: 32459957
Free article.
Clinical Trial.
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Multiplex LC-MS/MS Assays for Clinical Bioanalysis of MEDI4276, an Antibody-Drug Conjugate of Tubulysin Analogue Attached via Cleavable Linker to a Biparatopic Humanized Antibody against HER-2.
Faria M, Peay M, Lam B, Ma E, Yuan M, Waldron M, Mylott WR Jr, Liang M, Rosenbaum AI.
Faria M, et al. Among authors: peay m.
Antibodies (Basel). 2019 Jan 11;8(1):11. doi: 10.3390/antib8010011.
Antibodies (Basel). 2019.
PMID: 31544817
Free PMC article.
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Development and validation of HILIC-ESI/MS/MS methods for simultaneous quantitation of several antipsychotics in human plasma and blood.
De Meulder M, Waldron MP, Li L, Peay MG, Tingler MJ, Hidy BJ, Verhaeghe T, Jenkins RG.
De Meulder M, et al. Among authors: peay mg.
Bioanalysis. 2016 Apr;8(8):765-94. doi: 10.4155/bio.16.27. Epub 2016 Mar 23.
Bioanalysis. 2016.
PMID: 27005848
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