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The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease.
Neurobiol Dis. 2019 Jan;121:34-46. doi: 10.1016/j.nbd.2018.09.016. Epub 2018 Sep 17.
Neurobiol Dis. 2019.
PMID: 30236862
Free article.
A TOMM40/APOE allele encoding APOE-E3 predicts high likelihood of late-onset Alzheimer's disease in autopsy cases.
Soyal SM, Kwik M, Kalev O, Lenz S, Zara G, Strasser P, Patsch W, Weis S.
Soyal SM, et al. Among authors: kwik m.
Mol Genet Genomic Med. 2020 Aug;8(8):e1317. doi: 10.1002/mgg3.1317. Epub 2020 May 30.
Mol Genet Genomic Med. 2020.
PMID: 32472747
Free PMC article.
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Selective Activation of CNS and Reference PPARGC1A Promoters Is Associated with Distinct Gene Programs Relevant for Neurodegenerative Diseases.
Kwik M, Hainzl S, Oppelt J, Tichy B, Koller U, Bernardinelli E, Steiner M, Zara G, Nofziger C, Weis S, Paulmichl M, Dossena S, Patsch W, Soyal SM.
Kwik M, et al.
Int J Mol Sci. 2021 Mar 24;22(7):3296. doi: 10.3390/ijms22073296.
Int J Mol Sci. 2021.
PMID: 33804860
Free PMC article.
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The Expression of CNS-Specific PPARGC1A Transcripts Is Regulated by Hypoxia and a Variable GT Repeat Polymorphism.
Soyal SM, Bonova P, Kwik M, Zara G, Auer S, Scharler C, Strunk D, Nofziger C, Paulmichl M, Patsch W.
Soyal SM, et al. Among authors: kwik m.
Mol Neurobiol. 2020 Feb;57(2):752-764. doi: 10.1007/s12035-019-01731-5. Epub 2019 Aug 30.
Mol Neurobiol. 2020.
PMID: 31471878
Free PMC article.
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