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Page 1
Impaired IFNγ-Signaling and Mycobacterial Clearance in IFNγR1-Deficient Human iPSC-Derived Macrophages.
Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N. Neehus AL, et al. Among authors: kuhnel mp. Stem Cell Reports. 2018 Jan 9;10(1):7-16. doi: 10.1016/j.stemcr.2017.11.011. Epub 2017 Dec 14. Stem Cell Reports. 2018. PMID: 29249666 Free PMC article.
Recurrent HNSCC Harbor an Immunosuppressive Tumor Immune Microenvironment Suggesting Successful Tumor Immune Evasion.
Watermann C, Pasternack H, Idel C, Ribbat-Idel J, Brägelmann J, Kuppler P, Offermann A, Jonigk D, Kühnel MP, Schröck A, Dreyer E, Rosero C, Nathansen J, Dubrovska A, Tharun L, Kirfel J, Wollenberg B, Perner S, Krupar R. Watermann C, et al. Among authors: kuhnel mp. Clin Cancer Res. 2021 Jan 15;27(2):632-644. doi: 10.1158/1078-0432.CCR-20-0197. Epub 2020 Oct 27. Clin Cancer Res. 2021. PMID: 33109740
Analysis of tripartite motif (TRIM) family gene expression in prostate cancer bone metastases.
Offermann A, Kang D, Watermann C, Weingart A, Hupe MC, Saraji A, Stegmann-Frehse J, Kruper R, Schüle R, Pantel K, Taubert H, Duensing S, Culig Z, Aigner A, Klapper W, Jonigk D, Philipp Kühnel M, Merseburger AS, Kirfel J, Sailer V, Perner S. Offermann A, et al. Among authors: philipp kuhnel m. Carcinogenesis. 2021 Dec 31;42(12):1475-1484. doi: 10.1093/carcin/bgab083. Carcinogenesis. 2021. PMID: 34487169
Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.
Haake K, Neehus AL, Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova JL, Bustamante J, Lachmann N. Haake K, et al. Among authors: kuhnel mp. Cells. 2020 Feb 19;9(2):483. doi: 10.3390/cells9020483. Cells. 2020. PMID: 32093117 Free PMC article.
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections.
Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin AR, Brinkert K, Schott JW, Haake K, Kühnel MP, Glage S, Figueiredo C, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A, Lachmann N. Ackermann M, et al. Among authors: kuhnel mp. Nat Commun. 2018 Nov 30;9(1):5088. doi: 10.1038/s41467-018-07570-7. Nat Commun. 2018. PMID: 30504915 Free PMC article.
Cracking it - successful mRNA extraction for digital gene expression analysis from decalcified, formalin-fixed and paraffin-embedded bone tissue.
Saraji A, Offermann A, Stegmann-Frehse J, Hempel K, Kang D, Krupar R, Watermann C, Jonigk D, Kühnel MP, Kirfel J, Perner S, Sailer V. Saraji A, et al. Among authors: kuhnel mp. PLoS One. 2021 Sep 16;16(9):e0257416. doi: 10.1371/journal.pone.0257416. eCollection 2021. PLoS One. 2021. PMID: 34529723 Free PMC article.
Hematopoietic stem cell gene therapy for IFNγR1 deficiency protects mice from mycobacterial infections.
Hetzel M, Mucci A, Blank P, Nguyen AHH, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N. Hetzel M, et al. Among authors: kuhnel mp. Blood. 2018 Feb 1;131(5):533-545. doi: 10.1182/blood-2017-10-812859. Epub 2017 Dec 12. Blood. 2018. PMID: 29233822 Free article.
Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies.
Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer RA, Antonopoulos G, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D, Kühnel MP. Kellner M, et al. Among authors: kuhnel mp. Thorax. 2015 Dec;70(12):1197-8. doi: 10.1136/thoraxjnl-2015-207131. Epub 2015 Jun 24. Thorax. 2015. PMID: 26108569
14 results